Results 131 to 140 of about 1,616,838 (296)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Creative manipulation: a case study of confirmshaming as a deceptive design pattern

Creativity Studies
This research article explores the intersection between creativity and deceptive design patterns, focusing on the concept of confirmshaming within the broader framework of a creative society.
Milvydas Knyzelis
doaj   +1 more source

Variations of Martian surface albedo: Evidence for yearly dust deposition and removal [PDF]

The purpose is to determine the degree, spatial distribution and timing of the deposition and removal of dust storm fallout, and to relate the current patterns of dust deposition and removal to the long-term evolution of the Martian surface.
Christensen, Philip R.
core   +1 more source

Dark patterns and consumer vulnerability

Behavioural Public Policy
Abstract Dark patterns that manipulate consumer behaviour are now a pervasive feature of digital markets. Depending on the choice architecture utilised, they can affect the perception, behaviour and purchasing patterns of online consumers. Using a novel empirical design, we find strong evidence that individuals across all groups are susceptible to ...
Amit Zac, Yu-Chun Huang, Amédée von Moltke, Christopher Decker, Ariel Ezrachi   +4 more
openaire   +3 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Conceptualizing Discussions on the Dark Web: An Empirical Topic Modeling Approach

Complexity
Social networks on the Internet have become a home that attracts all types of human thinking to exchange knowledge and ideas and share businesses. On the other hand, it has also become a source for researchers to analyze this knowledge and frame it in ...
Randa Basheer, Bassel Alkhatib
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Magnetized LambdaCDM inhomogeneities and the cosmic dark ages

, 2011
Exact solutions of the perturbations equations in the magnetized LambdaCDM scenario are presented. They apply during the dark ages and, more specifically, after the baryons are freed from the drag of the photons.
Giovannini, Massimo
core