Results 121 to 130 of about 540,061 (294)

Dark Patterns: Eine interdisziplinäre Analyse

, 2023
Der Trendbegriff „Dark Patterns“ hat Konjunktur. Er ist ebenso omnipräsent wie interpreta-tionsoffen. Designmuster, die den Nutzer in eine verbraucherschädigende Richtung lenken sollen, stellen Wissenschaft, Regulierungsbehörden und den Gesetzgeber ...
Gertz, Michael, Martini, Mario (Prof., Dr. jur.), Timko, Christina, Seeliger, Paul   +3 more
core  

Obesity drives temporally distinct physical activity disruptions in mice under a fixed 24-h light-dark cycle

Scientific Reports
24-h cycles regulate activity and feeding behavior, and obesity and metabolic dysfunction may disrupt such rhythms. Here, using a fixed 24-h light-dark cycle, we investigate sex-specific diurnal physical activity patterns in obese and normal weight mice.
Abigail Usiyevich, Yufan Li, Reema Sharma, Kenny Arbuckle, Jay Shah, Bridget A. Matikainen-Ankney   +5 more
doaj   +1 more source

Examining the mechanisms linking Dark Triad traits to OCB through LMX and political skill: a comparative study of managerial and non-managerial levels

Frontiers in Psychology
PurposeThis study examines the relationship between perceived leaders’ Dark Triad personality traits (Machiavellianism, narcissism, and psychopathy) and followers’ organizational citizenship behavior (OCB). We explore how leader-member exchange (LMX) and
Abira Reizer, Aharon Tziner, Amos Drory
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Robust light-dark patterns and reduced amyloid load in an Alzheimer's disease transgenic mouse model. [PDF]

Sci Rep, 2020
Nagare R, Possidente B, Lagalwar S, Figueiro MG.   +3 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Dark Patterns as Disloyal Design

Lawmakers have started to regulate “dark patterns,” understood to be design practices meant to influence technology users’ decisions through manipulative or deceptive means.
Choffnes, David, Gunawan, Johanna, Hartzog, Woodrow, Wilson, Christo, Richards, Neil   +4 more
core   +2 more sources