Results 111 to 120 of about 152,438 (313)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Effect of auxins: (NAA, IAA), cytokinin BAP and culture conditions (light, darkness) on callus induction in cotyledons of tomato cultivar ‘Maskotka’ and the wild form of Lycopersicon peruvianum was investigated.
Danuta Rzepka-Plevneš +4 more
doaj
DARK ENERGY WITHOUT DARK ENERGY [PDF]
32 pages, 8 figures; Invited contribution to appear in the Proceedings of the Dark2007 Conference, Sydney, Australia, Sept 2007, eds H. Klapdor-Kleingrothaus and G.F. Lewis, (World Scientific, Singapore, 2008)
openaire +2 more sources
In the Darkness, Everything Went All Black
Konceptdesign och scenografi till operan In the Darkness, Everything Went All ...
Jalhed, Hedvig, +5 more
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
By focusing on two notions, shadows and darkness, which are both prominent in US hardboiled/noir fiction from the1920s to the 1960s, this article offers two readings of the genre, as (1) the reenactment of an epic/shamanic narrative of incursion into the
Benoît Tadié
doaj +1 more source
A Necessary Darkness 2017 - (commissioned by the Amsterdam Light Festival* in partnership with NEMO - the Dutch Museum of Science). a large scale projection on to the Renzo Piano designed ‘NEMO’ building (Oosterdok 2 Amsterdam) dusk - 11pm daily 30 ...
Lee, Rona
core
Darkness. The Dynamics of Darkness in the North [PDF]
Defining darkness can be an impossible exercise to explain absence, nothingness, and the absolute all at once. Darkness falls within a system of symbolic values where colours are ascribed to meanings that are related to one another.The relationship ...
Jóhannesson, Gunnar Thór +2 more
core
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Riverine caves are special habitats that are home to many aquatic and terrestrial species. Some Odonata species and their emerging are recorded at the entrance and in the twilight zones of subterranean habitats around the world. However, the emergence of
Pouria Ghelich Khani +2 more
doaj +1 more source

