Results 91 to 100 of about 152,438 (313)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

How Dark is ‘Dark’? Electromagnetic Interactions in the Dark Sector [PDF]

open access: yes, 2006
We review the physical and cosmological consequences of two possible electromagnetic couplings to the dark sector: (i) a neutral lightest dark-matter particle (LDP) with nonzero electric and/or magnetic dipole moments and (ii) a charged next-to-lightest dark-matter particle (NLDP) which decays to a neutral LDP.
openaire   +2 more sources

DARK MATTER AND DARK GAUGE FIELDS [PDF]

open access: yesDark Matter in Astroparticle and Particle Physics, 2008
Following the unexpected theoretical discovery of a mass dimension one fermionic quantum field of spin one half, we now present first results on two _local_ versions. The Dirac and Majorana fields of the standard model of particle physics are supplemented by their natural counterparts in the dark matter sector.
Ahluwalia, D. V.   +3 more
openaire   +2 more sources

Viewing Daughters of Darkness through the lens of Queer Fear

open access: yes, 2023
Leeds International Film Festival (LIFF) was founded in 1987 and is supported by Leeds City Council, West Yorkshire in the UK. "Queer Fear", which aims to chart queer communities’ lasting association with the horror genre, has been included in the ...
Broadhead, Samantha
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Weegee’s City Secrets

open access: yesE-REA, 2010
As a freelance photographer of crime, accidents, fires, and also of the recreational life of the city—scenes of violence and of pleasure—Weegee worked mainly at night and employed a powerful photoflash attachment to his press camera.
Alan TRACHTENBERG
doaj   +1 more source

“MEMORY BELIEVES BEFORE KNOWING REMEMBERS”: EVANESCENCE AND /OR ENDURANCE IN WILLIAM FAULKNER [PDF]

open access: yesUniversity of Bucharest Review. Literary and Cultural Studies Series, 2022
My paper focuses on one of William Faulkner’s masterpieces, Light in August (1932). Literary ambiguity employed at its best renders this text inexhaustible. Aspects of identity - race, gender, religion – may offer various approaches; yet, as I would like
Anca Peiu
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

"The fall of the house of Usher" : a master text for (Poe's) American Gothic

open access: yesJournal of English Studies, 2009
This paper analyses a selection of Poe’s fiction taking as a point of departure the contentions of critics such as Hillis Miller and Eric Savoy on the characteristics of American Gothic.
Marita Nadal
doaj   +1 more source

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