Results 121 to 130 of about 1,358,895 (382)

Igniting imagination through darkness: discovering fear and fantasy through shadows, silence and the invisible. [PDF]

, 2016
Darkness invites imagination. On the one hand, it creates intimacy. It has been observed by many artforms that we feel the need to close off our vision during intense emotional experiences, during dreaming, listening to music, or caressing our loved ones.
Jordaan, June, Slabbert, Barend
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

PYR/RCAR Receptors Contribute to Ozone-, Reduced Air Humidity-, Darkness-, and CO2-Induced Stomatal Regulation1[C][W][OA]

Plant Physiology, 2013
Signaling through abscisic acid PYR/RCAR receptors plays a fundamental role in controlling whole-plant stomatal conductance and affects stomatal closure in response to low air humidity, darkness, O3, and elevated CO2.
E. Merilo, K. Laanemets, Honghong Hu, Shaowu Xue, Liina Jakobson, I. Tulva, Miguel González-Guzmán, P. L. Rodriguez, J. Schroeder, M. Brosché, H. Kollist   +10 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

History, trauma, demystification and narration in the novels Darkness and Animal kingdom by David Albahari [PDF]

Baština
The paper explores the issues of history, trauma, demystification, and narration present in the novels Darkness and Animal Kingdom, written by the Serbian writer David Albahari. It begins with an introduction that discusses Albahari's literary opus, with
Kovačević Darko M.
doaj   +1 more source

Molecular and Photosynthetic Responses to Prolonged Darkness and Subsequent Acclimation to Re-Illumination in the Diatom Phaeodactylum tricornutum

PLoS ONE, 2013
Photosynthetic diatoms that live suspended throughout the water column will constantly be swept up and down by vertical mixing. When returned to the photic zone after experiencing longer periods in darkness, mechanisms exist that enable the diatoms both ...
M. Nymark, K. Valle, K. Hancke, P. Winge, Kjersti Andresen, G. Johnsen, A. Bones, Tore Brembu   +7 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Road to Transformation: Ascending from the Decade of Darkness [PDF]

, 2012
Nobody likes mistakes. Fewer yet like to revisit errors—to analyze, discuss or study them. They are often an embarrassment and remind us of our fallibility and shortcomings. It is always much easier to celebrate our achievements and successes—that leaves
Bentley, Bill, Horn, Bernd
core   +1 more source

Asymptotic Safety, Asymptotic Darkness, and the hoop conjecture in the extreme UV

, 2010
Assuming the hoop conjecture in classical general relativity and quantum mechanics, any observer who attempts to perform an experiment in an arbitrarily small region will be stymied by the formation of a black hole within the spatial domain of the ...
Basu, Sayandeb, Mattingly, David
core   +1 more source