Results 181 to 190 of about 1,358,895 (382)
CTA sensitivity on TeV scale dark matter models with complementary limits from direct detection [PDF]
, 2022 Chaimongkol Duangchan +10 more
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
American and British Studies Annual, 2010 “Now I lay me down to sleep, I pray the Lord my soul to keep; if I should die before I wake, I pray the Lord my soul to take.” As this well-known little prayer suggests, during actual sleep—while the conscious faculties are inoperative—the soul is at ...
Kathleen Dubs
doaj
Probing dark energy in the scope of a Bianchi type I spacetime [PDF]
, 2018 Hassan Amirhashchi
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Karanlık Risalesi: Felsefeden Mistisizme
EskiyeniGenelde olumsuzlama cihetinden aydınlığın/nurun zıttı olarak kabul edilen karanlık, bu niteliği ile aydınlığın olmadığı bir durumu betimliyor olsa da onun nurun en parlak hâlini ifade ettiğini söylemek de mümkündür.
Mehmet Murat Karakaya
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Vegetable ResearchThe biosynthesis of anthocyanin in plants is regulated by temperature, light, jasmonic acid (JA), among others. JASMONATE ZIM-DOMAIN (JAZ) proteins are critical repressors of the jasmonic acid (JA) pathway, the role of JAZ proteins on anthocyanin ...
Yue Wang +7 more
doaj +1 more source