Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
In this essay I examine the features of night, in particular, urban night. I try to highlight the epistemological divide between day and night, light and darkness.
Justin Winkler
doaj
Lignification in Scots Pine Callus as Reaction to Cultivation Conditions and Nutrient Medium [PDF]
The effect of nutrient medium composition and of the conditions of cultivation of Scots pine (Pinus sylvestris L.) callus on the morphology of its cells, the degree of their differentiation and lignification was studied. The morphological characteristics
G. F. Antonova+2 more
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Chronotype and response to training during the polar night: a pilot study
Background: An individual’s chronotype influences his or her physiological rhythms. Some studies have looked at the effect of time of day on the responses to exercise, but studies on the effect of long-term training are lacking. Objective: To report the
Jacopo Antonino Vitale+4 more
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The Binary Oppositions in Joseph Conrad's Novel Heart of Darkness
The novel Heart of Darkness is regarded as one of Joseph Conrad's highly skilled works and seen as an important tale written between the years of 1898 - 1899, and also viewed as an assault on imperialism and unethical behaviors of the European ...
أ.م.د هدى كاظم علوان
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The dark side of cosmology: Dark matter and dark energy [PDF]
A simple model with only six parameters (the age of the universe, the density of atoms, the density of matter, the amplitude of the initial fluctuations, the scale dependence of this amplitude, and the epoch of first star formation) fits all of our cosmological data . Although simple, this standard model is strange.
openaire +3 more sources
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Can UV light induce movement in cage-free laying hens?
SUMMARY: In recent years, more farms have been transitioning to cage-free systems as multiple states passed regulations banning use of conventional cages, and several large food service companies pledged to exclusively source cage-free eggs by 2025–2026.
A.V. Mendoza, S. Weimer, Z. Williams
doaj
History, trauma, demystification and narration in the novels Darkness and Animal kingdom by David Albahari [PDF]
The paper explores the issues of history, trauma, demystification, and narration present in the novels Darkness and Animal Kingdom, written by the Serbian writer David Albahari. It begins with an introduction that discusses Albahari's literary opus, with
Kovačević Darko M.
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Effect of photoperiod on somatic embryogenesis in different organs of chickpea (Cicer arietinum L.) [PDF]
Introduction Somatic embryogenesis is an efficient platform for the generation of transgenic plants and synthetic seeds (Kiran et al., 2005). Somatic embryo’s growth and development were influenced by different factors, including photoperiod, genotype as
ALI AKBAR MOZAFARI, Kazhal Kamangar
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