Results 61 to 70 of about 10,983 (287)
Advances in Applied Mathematics, 2023 We analyze a game introduced by Andy Niedermaier, where $p$ players take turns throwing a dart at a dartboard. A player is eliminated unless his dart lands closer to the center than all previously thrown darts, in which case he goes to the back of the line, until only one player remains.
openaire +4 more sources
IPMI-ICNS-UKE/DARTS: DARTS FIMMU 2024 release
<p>This release is generated as corresponding to the following publication: Woelk L-M, et al. "DARTS: an open-source Python pipeline for Ca2+ microdomain analysis in live cell imaging data." Front. Immunol. 14:1299435.
DejanKov2901 +4 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
, 2016 We formalize sampling a function using k -d darts. A k -d Dart is a set of independent, mutually orthogonal, k -dimensional hyperplanes called k -d flats. A dart has d choose k flats, aligned with the coordinate axes for efficiency.
Mitchell, Scott A +5 more
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How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Jurnal Inovasi Pendidikan Kimia, 2019 Understanding the chemistry concept should be demonstrated by the ability to transfer and connect levels of chemical representation. This study aimed to produce DARTs-worksheets containing multiple levels of representation as learning media to improve ...
Muhamad Imaduddin, Sri Haryani
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
PLoS ONE, 2012 BackgroundObesity is highly associated with elevated serum triglycerides, hepatic steatosis and type 2 diabetes (T2D). The I148M (rs738409) genetic variant of patatin-like phospholipase domain-containing 3 gene (PNPLA3) is known to modulate hepatic ...
Colin N A Palmer +21 more
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