Clinical Evaluation of Drug-Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P-gp Pathways. [PDF]
Arora P +4 more
europepmc +1 more source
A Systematic Review and Classification of the Effects of P-glycoprotein Inhibitors and Inducers in Humans, Using Digoxin, Fexofenadine, and Dabigatran as Probe Drugs. [PDF]
Coumau C, Csajka C.
europepmc +1 more source
Mapping the Gut Microbiota Composition in the Context of Raltegravir, Dolutegravir, and Bictegravir-A Scoping Review. [PDF]
Gáspár Z, Lakatos B.
europepmc +1 more source
DEFINE: A Prospective, Randomized, Phase 4 Trial to Assess a Protease Inhibitor-Based Regimen Switch Strategy to Manage Integrase Inhibitor-Related Weight Gain. [PDF]
Anderson D +8 more
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A novel measure of antiretroviral activity in CSF and association with HIV persistence and cognitive function. [PDF]
Avedissian SN +7 more
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Dolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV
BACKGROUND The World Health Organization recommends dolutegravir with two nucleoside reverse-transcriptase inhibitors (NRTIs) for second-line treatment of human immunodeficiency virus type 1 (HIV-1) infection. Evidence is limited for the efficacy of this
Stephen Ian Walimbwa +2 more
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Lack of antiviral activity of darunavir against SARS-CoV-2
Given the high need and the absence of specific antivirals for treatment of COVID-19 (the disease caused by severe acute respiratory syndrome-associated coronavirus-2 [SARS-CoV-2]), human immunodeficiency virus (HIV) protease inhibitors are being ...
Denisa Bojkova +2 more
exaly +2 more sources
A major challenge in the management of antiretroviral therapy (ART) is to improve the patient’s adherence, reducing the burden caused by the high number of drugs that compose the treatment regimens for human immunodeficiency virus positive (HIV ...
Nicoleta Negrut, Simona Bungau
exaly +2 more sources
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Ritonavir and darunavir were examined using a ultra-performance liquid chromatography (UPLC) approach in pharmaceutical dosage forms. The small number of analytical studies that are currently available do not demonstrate the method's stability or nature.
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