Results 121 to 130 of about 8,395,067 (251)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 2014 Salah satu penyebab banjir dan erosi adalah kondisi biofisik di bagian hulu Daerah Aliran Sungai (DAS) yang sudah tidak dapat mendukung fungsi hidrologis DAS dengan baik, sehingga perlu dilakukan upaya-upaya penerapan teknik konservasi tanah yang tepat ...
Firdaus, Gunadi
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
International Archives of Otorhinolaryngology, 2020 Marilia D'Elboux Guimarães Brescia +5 more
doaj +1 more source
Therapeutics and Clinical Risk Management, 2018 Naza Mohammed Ali Mahmood,1 Saad Abdulrahman Hussain,2 Raouf Rahim Mirza3 1Department of Pharmacology and Toxicology, College of Pharmacy, University of Sulaimani, Kurdistan Region, Iraq; 2Department of Pharmacology and Toxicology, Faculty of Pharmacy ...
Mahmood NMA, Hussain SA, Mirza RR
doaj
A formação das pontes de hidrogênio
, 2014 Discorre sobre a formação das ligações de hidrogênio, apresentando suas características e formaçãoEnsino Médio::QuímicaEnsino Médio ...
Chagas, Evelize Folly das
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A importância da contabilidade no processo decisório das micro e pequenas empresas [PDF]
, 2007 TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisEste trabalho desenvolve um estudo sobre a importância da Contabilidade no processo decisório das Micro e Pequenas Empresas, mostrando a ...
Virgílio, Maria das Graças
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A formação das pontes de hidrogênio
, 2011 Discorre sobre a formação das ligações de hidrogênio, apresentando suas características e formaçãoEnsino Médio::QuímicaEnsino Médio ...
Chagas, Evelize Folly das
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