Results 101 to 110 of about 8,395,067 (251)

The Association of Anti-CCP and Disease Activity in Rheumatoid Arthritis

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Purpose: To determine the value of Anti-CCP as predictor for disease activity in rheumatoid arthritis assessed by DAS-28, and to find the effect of smoking on disease activity in rheumatoid arthritis.
Raouf Rahim Merza, Dana Mohammed Tofiq, Najlaa Naser Radhi, Hawar Ali Ehsan Kaka Khan   +3 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Study of the Association Between MTHFR Polymorphism (rs1801133) and the Outcome of Methotrexate Treatment in Rheumatoid Arthritis Patients [PDF]

Ain Shams Medical Journal
Background: Rheumatoid arthritis is a long-term autoimmune condition that impairs joint function and drastically lowers quality of life. Methotrexate, one of the disease-modifying anti-rheumatic drugs acts differently depending on the genotypes being ...
marium fathi, karim shahin, amani abdel ghani, marwa raafat, fatma badr, Noha Mohamed   +5 more
doaj   +1 more source

Exploring the relation between impairment rating by DAS-28 and body

, 2018
Hand problems associated with rheumatoid arthritis lead to subjective impairment, activity limitation, and restrictions on participation. This relation is very complex. Assessment of individuals' activities is important to determine how hand problems affect not only body functions but also daily life activities.
Kabul, EG, Aslan, UB, Calik, BB, Tasci, M, Cobankara, V   +4 more
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A IMPORTÂNCIA DA INFORMAÇÃO FINANCEIRA NAS EMPRESAS PORTUGUESAS: O JUSTO VALOR DO ATIVO FIXO TANGÍVEL [PDF]

, 2016
RESUMO Motivação: A União Europeia preconizou, através do Regulamento 1606/2002, a obrigatoriedade da adoção das normas do IASB nas contas consolidadas de todas as empresas cotadas em bolsas europeias, a partir de 1 de Janeiro de 2005.
Paiva, Inna, Silva, Ana Lorga, Paiva, Inna Choban de Sousa, Silva, Marisa, Silva, Ana Lorga da, Silva, Mariza   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Correlation of Body Mass Index and Disease Activity Score (DAS-28) in Patients with Rheumatoid Arthritis

National Journal of Community Medicine
Background: Rheumatoid Arthritis (RA) is the most common autoimmune disease. RA can cause permanent deformity and loss of productivity. The primary objective of the study was to evaluate the relationship of BMI with Disease Activity Score in RA patients.
Nishtha Agarwal, Shweta Dubey, Sanjeev Kapoor, Shriram Garg, AN Malaviya, Puja Nagpal   +5 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A Cross-Sectional Study of Depression in Rheumatoid Arthritis Patients at a Tertiary Care Center

Journal of Pharmacy and Bioallied Sciences
Background: Rheumatoid arthritis (RA) is a chronic autoimmune condition often linked with depression, worsening symptoms, and lowering the quality of life.
Hansraj Parmar, Prakash Joshi, Reena Singh, Sachin Parmar, Ranjana Sharma   +4 more
doaj   +1 more source