Results 81 to 90 of about 8,395,067 (251)
A formação das pontes de hidrogênio
Discorre sobre a formação das ligações de hidrogênio, apresentando suas características e formaçãoEnsino Médio::QuímicaEnsino Médio ...
Chagas, Evelize Folly das
core +2 more sources
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
The article presents 3 cohorts with early rheumatoid arthritis in patients aged 50 years and older with a disease duration from 1.5 months to 1 year. To establish a diagnosis, the classification criteria of its period were applied to each of the cohorts:
A. M. Satybaldyev +16 more
doaj
Background: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder characterized by synovial inflammation, joint destruction, and significant disability. Psychological factors, particularly depression and anxiety, are prevalent among RA patients and can impact disease management and treatment adherence.
null Hussain Shakeel +4 more
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Aim of study: To assess the efficacy and safety of using anti-tumor necrosis factor-α (TNF-α), Etanercept (ETN) in treatment of children and adolescents with Juvenile Idiopathic arthritis (JIA). Patients and methods: This retrospective cohort study included 18 children and adolescents who were diagnosed as JIA and treated with anti-tumor necrosis ...
Rasha Abdel-Raouf Afifi +3 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

