Results 81 to 90 of about 46,296 (251)
Health-related quality of life and disease activity in rheumatoid arthritis
Journal of Research in Medical Sciences, 2011 Background: The present study sought to 1) investigate the degrees of correlations between different disease activity scores (DASs) and health-related quality of life (HRQoL), and 2) determine if DASs correlate with either physical or mental HRQoL ...
Gholam Hossein Alishiri +6 more
doaj
Ulusal Romatoloji DergisiObjective: Patients with rheumatoid arthritis (RA) are generally seropositive, but 15-20% of patients with RA may be seronegative. Diagnosing patients with RA sometimes requires long and challenging research, and new diagnostic biomarkers are needed ...
Gizem Özan +11 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Jurnal Pendidikan IndonesiaArtritis Reumatoid (AR) merupakan penyakit inflamasi kronik yang berdampak pada fungsi fisik, kondisi mental, dan kualitas hidup pasien. Hubungan antara tingkat aktivitas penyakit dan penanda inflamasi seperti C-Reactive Protein (CRP) dengan kualitas hidup masih menunjukkan hasil yang bervariasi.
Danni Frederiko Asido Sirait +3 more
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Turkish Journal of Gastroenterology, 2013 Objectives: This study aims to investigate possible effects of Ramadan month of fasting on disease activity in rheumatoid arthritis (RA) patients. Patients and methods: Between January 2010 and December 2011, 71 patients with RA who were scheduled ...
Mohd Shahrir Mohamed SAID +6 more
doaj
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Cardiovascular risk in rheumatoid arthritis: a narrative review
Revista de la Facultad de Ciencias de la Salud, 2017 Rheumatoid arthritis (RA) is a chronic autoimmune disease with an especially articular involvement that is associated with an exponential increase in cardiovascular risk (CVR).
Manuel Felipe Cáceres Acosta +3 more
doaj +2 more sources
BMC Infectious DiseasesObjective The distribution of peripheral blood lymphocytes may change due to the influence of diseases. This study aims to investigate the impact of Hepatitis B virus (HBV) infection on the distribution of peripheral blood lymphocyte subsets in patients ...
Lijia Shao, Lihong Shen, Junqi Wu
doaj +1 more source