Gender stratified adjustment of the DAS28-CRP improves inter-score agreement with the DAS28-ESR in rheumatoid arthritis [PDF]
Abstract Objectives To evaluate determinants of discordance between DAS28-ESR and DAS28-CRP and resulting impact on disease activity stratification in RA. Methods Paired DAS28-ESR and DAS28-CRP readings (n = 31 074 ...
Hamann, Philip D.H. +5 more
core +15 more sources
Look Beyond the Disease Activity Score of 28 Joints (DAS28): Tender Points Influence the DAS28 in Patients with Rheumatoid Arthritis [PDF]
Objective.To explore the influence of tender points (TP) on the Disease Activity Score assessing 28 joints (DAS28) in patients with rheumatoid arthritis (RA).Methods.In 200 consecutive patients with RA from the outpatient clinic, DAS28 and its components, tender and swollen joint counts (TJC, SJC, respectively), visual analog scale (VAS) for patient’s ...
Ton, Evelien +8 more
core +4 more sources
DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment [PDF]
AbstractThis study is based on an expanded access program in which 511 patients suffering from active refractory rheumatoid arthritis (RA) were treated with intravenous infusions of infliximab (3 mg/kg+methotrexate (MTX)) at weeks 0, 2, 6 and every 8 weeks thereafter.
Vander Cruyssen, Bert +15 more
core +9 more sources
Validation of methods for converting the original Disease Activity Score (DAS) to the DAS28 [PDF]
The Disease Activity Score (DAS) is integral in tailoring the clinical management of rheumatoid arthritis (RA) patients and is an important measure in clinical research. Different versions have been developed over the years to improve reliability and ease of use.
Lewis Carpenter +6 more
core +8 more sources
Interpretation of DAS28 and its components in the assessment of inflammatory and non-inflammatory aspects of rheumatoid arthritis [PDF]
Background DAS28 is interpreted as the inflammatory disease activity of RA. Non-inflammatory pain mechanisms can confound assessment. We aimed to examine the use of DAS28 components or DAS28-derived measures that have been published as indices of non ...
Daniel F. McWilliams +5 more
doaj +3 more sources
Objective: to study the effect of neuropathic pain symptoms (SNP) on the clinical manifestations of rheumatoid arthritis (RA) in patients with moderate or high disease activity.Patients and methods.
E. Yu. Polishchuk +4 more
doaj +1 more source
DAS28-ESR values and serum IFX concentrations in responders and non-responders.
(A) DAS28-ESR values at baseline and at IFX measurement point. Responders (open circle) represent patients with “good or moderate response” and non-responders (closed circle) represent those with “no response” based on the European League Against ...
Shunsaku Nakagawa (430323) +20 more
core +1 more source
Clinical response to methotrexate (MT) therapy in rheumatoid arthritis (RA) can be predicted on the basis of some single nucleotide polymorphisms (SNPs) of genes, involved in folate metabolism.
M. Yu. Krylov +2 more
doaj +1 more source
The paper presents three cohorts of patients with early rheumatoid arthritis (RA) who fell ill at 50 years or older and had a disease duration of 1.5 months to 1 year.
A. M. Satybaldyev +15 more
doaj +1 more source
Objectives: One of the most prevalent autoimmune disease globally, rheumatoid arthritis (RA) is caused by interplay of multiple inflammatory mediators in specific joints. Altered redox balance is one of the key factors in pathophysiology of RA.
Kaushik Mukhopadhyay +5 more
doaj +1 more source

