Results 31 to 40 of about 50 (48)

AB0325 Comparison of Activity Score DAS28-ESR and DAS28 -CRP in Patients with Rheumatoid Arthritis

Annals of the Rheumatic Diseases, 2014
Objectives To compare the disease activity score (DAS)28- ESR versus DAS28 -CRP, and to determine the factors that might influence their difference. Methods Patients with RA were included in a cross-sectional study. We have collected the demographic characteristics and the characteristics of the RA: duration of evolution, morning stiffness in ...
I. Ben Slama, F. Allali, S. El Kabbaj, T. Lakhdar, L. Medrare, A. Ngeuleu, H. Rkain, N. Hajjaj-Hassouni   +7 more
openaire   +1 more source

Revising DAS28 scores for remission in rheumatoid arthritis

Clinical Rheumatology, 2014
Current initiatives to treat rheumatoid arthritis (RA) to target remission have resulted in the widespread use of composite outcome measures to quantify disease activity. Simplified Disease Activity Index (SDAI) ≤3.3 is the gold standard of remission. Previous work has suggested that the remission threshold of DAS28-ESR or DAS28-CRP ≤2.6 is known to be
Sheehy, Claire, Evans, Verity, Hasthorpe, Heather, Mukhtyar, Chetan   +3 more
openaire   +3 more sources

THU0073 DAS28-CRP and DAS28-ESR Cutoffs for High Disease Activity in Rheumatoid Arthritis Are Not Interchangeable

Annals of the Rheumatic Diseases, 2016
Background Rheumatoid arthritis (RA) clinical trials have shown that mean DAS28 calculated using C-reactive protein (CRP) is lower than DAS28 calculated using erythrocyte sedimentation rate (ESR). We demonstrated that DAS28-CRP cutoffs equivalent to DAS28-ESR for remission and low disease activity (LDA) were 2.4 and 2.9, respectively, rather than 2.6 ...
R.M. Fleischmann, D. van der Heijde, P.V. Gardiner, A. Szumski, L. Marshall, E. Bananis   +5 more
openaire   +1 more source

OP0174 The Development of The Modified DAS28-CRP To Improve Agreement with DAS28-ESR and Ensure Appropriate Disease Activity Stratification in RA

Annals of the Rheumatic Diseases, 2016
Background Disease activity in rheumatoid arthritis (RA) has traditionally been measured using the 28-joint count disease activity score (DAS28) using ESR. Use of DAS28 with CRP in place of ESR is increasing. Evidence suggests these scores are not truly interchangeable and agreement varies dependant on disease activity. This study uses the BSRBR-RA to
P.D.H. Hamann, K. Hyrich, A. Jobling, N. McHugh, G. Shaddick, J. Pauling   +5 more
openaire   +1 more source

Effect of the Coexistence of Fibromyalgia in the DAS28 Index in Women With Rheumatoid Arthritis

Reumatología Clínica (English Edition), 2008
To compare the effect of coexisting fibromyalgia in DAS28 in RA female patients.Fifty-three RA women seen consecutively in an outpatient rheumatology clinic were included and classified according to the presence (9 women) or absence (44 women) of fibromyalgia.
Daniel, Roig Vilaseca, Carmen, Hoces Otero   +1 more
openaire   +2 more sources

THU0235 Global Tenderness and Anxiety/Depression as a Component of the DAS28

Annals of the Rheumatic Diseases, 2014
Background The DAS28 (disease activity score 28) was created for the purpose of quantifying and comparing inflammatory processes for patients with Rheumatoid Arthritis. One of the four components measured is a 28 joint tender count. The objectivity of this marker is unclear.
A. Pervez, S. Kelly, B. Kidd
openaire   +1 more source

Remission in rheumatoid arthritis: missing objectives by using inadequate DAS28 targets

Nature Reviews Rheumatology, 2019
For too long, the definition of ‘remission’ in rheumatoid arthritis has been distorted by the widespread use of an inadequate tool, with consequences for clinical care and for making sense of clinical trial data. Has the time come to move away from DAS28-defined remission?
Daniel Aletaha, Josef S. Smolen
openaire   +2 more sources

FRI0573 Integration of Time-Averaged DAS28 Fits Better Joint Destruction In Rheumatoid Arthritis Than One-Time DAS28 and Identifies A Significant Joint-Destructive Association of HLA-DRB1*04:05 Which is Independent of ACPA and DAS28

Annals of the Rheumatic Diseases, 2016
Background Disease Activity Score 28 (DAS28) is one of correlates of joint destruction in rheumatoid arthritis (RA) as well as genetic components, RA-related autoantibodies, and disease duration. Joint destruction is considered to reflect the cumulative history of the disease activities, but one-time DAS28 is used in many studies.
H. Tsuji, C. Terao, K. Yano, K. Ikari, M. Hashimoto, M. Furu, H. Ito, T. Fujii, W. Yamamoto, N. Yamakawa, K. Ohmura, A. Taniguchi, S. Momohara, H. Yamanaka, F. Matsuda, T. Mimori   +15 more
openaire   +1 more source

AB0539 Comparison of RA patients in tocilizumab (TCZ) therapy who showed only DAS28(ESR) remission and both DAS28-ESR and SDAI remission

Annals of the Rheumatic Diseases, 2012
Background The TCZ treatment for RA is known that there is a discrepancy within DAS remission and SDAI remission rate cause by the weight of gravity of acute phase reactants. Especially TCZ strongly inhibits CRP which produced by the liver through the IL-6. Therefore even if we meet to the DAS remission; we come across the cases occasionally who have
I. Yokoe, H. Kobayashi, H. Sato, A. Nishiwaki   +3 more
openaire   +1 more source

FRI0024 Contribution of the Individual Components of the Disease Activity Score (DAS28) to the Total DAS28 Score among Responders and Non-Responders to Biological Therapy for Rheumatoid Arthritis

Annals of the Rheumatic Diseases, 2014
Background The commonly used Disease Activity Score based on 28 joints (DAS28) is a composite index composed of two somewhat subjective components (tender joint count and visual analogue scale general well-being) and two more objective components (swollen joint count and erythrocyte sedimentation rate).
M.S. Jurgens, C.L. Overman, J.W. Jacobs, R. Geenen, B.V. Cuppen, A.C. Marijnissen, J.W. Bijlsma, P.M. Welsing, F.P. Lafeber, J.M. van Laar   +9 more
openaire   +1 more source