Results 91 to 100 of about 54,207 (313)
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
Internal Medicine, 2020 We report the case of a 56-year-old man with chronic myeloid leukemia (CML) who developed dasatinib-induced interstitial lung disease (ILD) 7 years after starting dasatinib, a BCR-ABL1 inhibitor. The patient presented with dyspnea. Chest imaging showed diffuse ground-glass opacities.
Keitaro Okuda +19 more
openaire +4 more sources
Management of imatinib-resistant CML patients [PDF]
, 2007 Imatinib has had marked impact on outcomes in chronic myelogenous leukemia (CML) patients for all stages of the disease and is endorsed by international treatment guidelines as the first line option.
Branford S +21 more
core +1 more source
Dasatinib in recurrent glioblastoma: failure as a teacher [PDF]
Neuro-Oncology, 2015 The Radiation Therapy Oncology Group (RTOG) trial 0627 evaluated the efficacy of dasatinib in recurrent glioblastoma. Why was dasatinib, of unequivocal benefit in Philadelphia chromosome– positive leukemia and so promising in gastrointestinal stromal tumor, of interest in glioblastoma? And why did the drug fail? Dasatinib is a potent oral multitargeted
Jann N. Sarkaria, David Schiff
openaire +3 more sources
Triple negative breast cancer: new perspectives for targeted therapies [PDF]
, 2015 Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors.
Caruso, Davide +8 more
core +1 more source
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.This review involves a comprehensive study on the diverse applications of the magnetic layered double hydroxides (LDHs) including their catalytic performances, as well as, environmental and biological functions. Moreover, different strategies utilized for the synthesis of LDH‐based composites are described.
Mohammad Mavvaji +2 more
wiley +1 more source
Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice. [PDF]
PLoS ONE, 2014 This study aimed to determine whether the multi-kinase inhibitor dasatinib would provide an effective therapy for myeloproliferative diseases (MPDs) involving c-Cbl mutations.
Johanna M Duyvestyn +6 more
doaj +1 more source
Dasatinib–SIK2 Binding Elucidated by Homology Modeling, Molecular Docking, and Dynamics Simulations
ACS Omega, 2021 Salt-inducible kinases (SIKs) are calcium/calmodulin-dependent protein kinase (CAMK)-like (CAMKL) family members implicated in insulin signal transduction, metabolic regulation, inflammatory response, and other processes.
Mingsong Shi +5 more
semanticscholar +1 more source
Transforming growth factor β signaling overcomes dasatinib resistance in lung cancer. [PDF]
PLoS ONE, 2014 Lung cancer is the second most common cancer and the leading cause of cancer-related deaths. Despite recent advances in the development of targeted therapies, patients with advanced disease remain incurable, mostly because metastatic non-small cell lung ...
Edna Gordian +8 more
doaj +1 more source