Results 91 to 100 of about 28,091,365 (305)
Data driven selection of consensus docking pipelines for structure based hit identification
npj Drug DiscoveryStructure-based virtual screening (SBVS) is a cornerstone of computer-aided drug design, yet its success depends on selecting a combination of docking tools, scoring function (SF), and ranking strategies.
Hamza Agha +6 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Decomposing heterogeneity in disease progression speeds and pathways
npj Digital MedicineUnderstanding why patients with the same diagnosis exhibit markedly different disease progression—some rapidly, others slowly, with distinct symptom patterns—remains a major challenge in medicine.
Yuichiro Yada, Honda Naoki
doaj +1 more source
Zero-Shot Learning for Sustainable Municipal Waste Classification
RecyclingAutomated waste classification is an essential step toward efficient recycling and waste management. Traditional deep learning models, such as convolutional neural networks, rely on extensive labeled datasets to achieve high accuracy.
Dishant Mewada +5 more
doaj +1 more source
Data-driven pre-design tool for Centrifugal Compressor - Supplementary data
, 2018 This dataset is linked to the following paper: V. Mounier, C. Picard, J. Schiffmann. Data-Driven Predesign Tool for Small-Scale Centrifugal Compressor in Refrigeration. ASME. J. Eng. Gas Turbines Power. 2018;140(12):121011-121011-8. doi:10.1115/1.4040845.
Mounier, V (via Mendeley Data) +1 more
core +1 more source
The Rise of Data-Driven Governance
, 2020 The world appears to be overflowing with data, thanks to rapid developments in technology over the past ten to fifteen years. It is increasingly argued that data-driven knowledge is capable of changing the ways in which we understand the world and also ...
Chandler, D.
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Data-driven interactive quadrangulation
ACM Transactions on Graphics, 2015 We propose an interactive quadrangulation method based on a large collection of patterns that are learned from models manually designed by artists. The patterns are distilled into compact quadrangulation rules and stored in a database. At run-time, the user draws strokes to define patches and desired edge flows, and the system queries the database to ...
Giorgio Marcias +6 more
openaire +5 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source