Results 101 to 110 of about 26,722,291 (305)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Application of Vision Transformers to Contamination Detection in Densely Cluttered Waste Scenes

IEEE Open Journal of the Computer Society
With the increasing global waste production, there is a rising need for improved waste management solutions to address this growing issue. In the United States, less than 35% of recyclable materials are actually recycled, leading to higher levels ...
Dishant Mewada, Cathaoir Agnew, Eoin M. Grua, Ciaran Eising, Patrick Denny, Mark Heffernan, Ken Tierney, Pepijn Van de Ven, Anthony Scanlan   +8 more
doaj   +1 more source

Developing Social Interaction Skills with Game Technology

SISFORMA, 2019
Socialization is an essential process in human living. Human is a social creature which can not living without the help of others, so human needs friends to communicate and interact with each others to make a living better. Through a socialization, human
Lidya Oktorina Kusuma Sakti, Septyana Hardianti Yunanto   +1 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Data-Driven Model Order Reduction for Magnetostatic Problem Coupled with Circuit Equations [PDF]

, 2017
Among the model order reduction techniques, the Proper Orthogonal Decomposition (POD) has shown its efficiency to solve magnetostatic and magneto-quasistatic problems in the time domain.
A. Pierquin, Pierquin, A., S. Clenet, PIERQUIN, Antoine, T. Henneron, CLENET, stephane, Clenet, S., HENNERON, Thomas   +7 more
core   +1 more source

Regional impacts of solar radiation modification on surface temperature and precipitation in Mainland Southeast Asia and the adjacent oceans

Scientific Reports
Solar radiation modification (SRM) has been proposed to temporarily reduce anthropogenic warming. This study presents an assessment of the regional impacts of SRM via solar dimming and stratospheric aerosol injection (SAI) on temperature and ...
Pornampai Narenpitak, Siriwat Kongkulsiri, Saifhon Tomkratoke, Sirod Sirisup   +3 more
doaj   +1 more source

Unveiling the Digital Phenotype of Physical Activity Behavior in Community-Dwelling Older Adults Using Machine Learning

Bioengineering
Physical activity (PA) is an important factor for maintaining health and well-being, especially in older adults. This study aims to apply machine learning methods to predict PA patterns and identify key factors influencing these behaviors among community-
Anas Abdulghani, Kim Daniels, Bruno Bonnechère   +2 more
doaj   +1 more source

Data-Driven Edu Chatbots

Companion Proceedings of The 2019 World Wide Web Conference, 2019
There are many online courses and contents on the web, so each learner can find the best one and choose it. However, sometimes many online courses are poorly accessible due to the limits of the search engines on the web. The advent of intelligent systems, and online Chatbots, in particular, has brought improvement in various fields.
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source