Results 101 to 110 of about 28,091,365 (305)

Assessing the current landscape of AI and sustainability literature: identifying key trends, addressing gaps and challenges

Journal of Big Data
The United Nations’ 17 Sustainable Development Goals stress the importance of global and local efforts to address inequalities and implement sustainability.
Shailesh Tripathi, Nadine Bachmann, Manuel Brunner, Ziad Rizk, Herbert Jodlbauer   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Data-Driven Learning

Data-driven learning (DDL) is a pedagogical approach which involves letting students use corpus data to help them gain knowledge of a target language. In this article, various ways of doing DDL are presented, depending on whether it is carried out in a direct or indirect manner, what corpora are used and what types of searches are performed.
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Self Healing of a Mixed Autonomy Traffic System Using Reinforcement Learning and Attention

IEEE Open Journal of Intelligent Transportation Systems
As urban traffic becomes increasingly complex with the integration of connected and autonomous vehicles alongside human-driven vehicles, there is a critical need for adaptive traffic management systems capable of self-healing in response to disruptions ...
Safia Fatima, Kai Olav Ellefsen, Leon Moonen   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Data‐Driven Polyoxometalate Chemistry

Chemistry – A European Journal
AbstractPolyoxometalates (POMs) are nanoscale, structurally versatile metal–oxo clusters with emerging applications in sustainability, energy, nanoelectronics, and life science technologies. Owing to their structural complexity, some all‐inorganic POMs are often perceived as serendipitous outcomes from self‐assembly processes, which poses challenges ...
Kondinski, Aleksandar, Gumerova, Nadiia, Rompel, Annette, Falcaro, Paolo, Schreck, Tobias   +4 more
openaire   +2 more sources

Application of Vision Transformers to Contamination Detection in Densely Cluttered Waste Scenes

IEEE Open Journal of the Computer Society
With the increasing global waste production, there is a rising need for improved waste management solutions to address this growing issue. In the United States, less than 35% of recyclable materials are actually recycled, leading to higher levels ...
Dishant Mewada, Cathaoir Agnew, Eoin M. Grua, Ciaran Eising, Patrick Denny, Mark Heffernan, Ken Tierney, Pepijn Van de Ven, Anthony Scanlan   +8 more
doaj   +1 more source