Results 121 to 130 of about 26,722,291 (305)

Study of Program Memory for Data Driven Processor Qfa-0 [PDF]

, 1998
To realize highly parallel processor, we are studying about data-driven processor Qfa-0. Qfa-0 is made up of self-timed elastic transfer architectures,which is suitable for the ULSI design. Access de1ay of the program memory(PM) affects throughput of the
SAITOH, Kazuhiro, 浅田, 勝彦, ASADA, Katsuhiko, 齋藤, 和宏, 荒木, 新一郎, ARAKI, Shin-ichirou   +5 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Data-driven combinatorial optimization

Tong, GuangmoCombinatorial optimization problems, particularly those within the NP-hard and NP-complete classes, pose significant challenges due to their believed intractability in polynomial time.
Samizadeh, Mina
core   +1 more source

Machine learning estimates for G20 subnational urban GHG emissions from 2000–2020

Scientific Data
Reliable, comparable greenhouse gas (GHG) emissions data at the subnational level remain scarce, despite growing expectations for cities and regions to lead on climate action. Inconsistent reporting, methodological variation, and limited coverage of self-
Ying Yu, Xuewei Wang, Diego Manya, Angel Hsu   +3 more
doaj   +1 more source

Data-Driven Chinese Walls.

, 2018
Security policy and access control models are often based on qualitative attributes, e.g. security labels, cryptographic credentials. In this paper, we enrich one such model, namely the Chinese Walls model, with quantitative attributes derived from data. Therefore, we advocate a data-driven approach that considers a quantitative definition of access we
Gulsum Akkuzu, Benjamin Aziz
openaire   +4 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Evaluating and addressing demographic disparities in medical large language models: a systematic review

International Journal for Equity in Health
Background Large language models are increasingly evaluated for use in healthcare. However, concerns about their impact on disparities persist. This study reviews current research on demographic biases in large language models to identify prevalent bias ...
Mahmud Omar, Vera Sorin, Reem Agbareia, Donald U. Apakama, Ali Soroush, Ankit Sakhuja, Robert Freeman, Carol R. Horowitz, Lynne D. Richardson, Girish N. Nadkarni, Eyal Klang   +10 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source