Results 121 to 130 of about 19,419,888 (317)

Data driven ontology evaluation [PDF]

open access: yes, 2004
The evaluation of ontologies is vital for the growth of the Semantic Web. We consider a number of problems in evaluating a knowledge artifact like an ontology. We propose in this paper that one approach to ontology evaluation should be corpus or data driven. A corpus is the most accessible form of knowledge and its use allows a measure to be derived of
Brewster, Christopher   +3 more
openaire   +2 more sources

Data-driven Technologies : Challenges for Privacy and Data Protection Law

open access: yes
Data-driven technologies introduce new privacy risks that are currently not (explicitly) addressed by European data protection law. Against this backdrop, the chapter discusses the general conceptual shortcomings of the GDPR, followed by an overview of ...
Ebers, Martin,, Sein, Karin,
core  

Large-scale data-driven financial risk assessment

open access: yes, 2019
The state of data in finance makes near real-time and consistent assessment of financial risks almost impossible today. The aggregate measures produced by traditional methods are rigid, infrequent, and not available when needed.
Breymann, Wolfgang   +9 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Evaluating and addressing demographic disparities in medical large language models: a systematic review

open access: yesInternational Journal for Equity in Health
Background Large language models are increasingly evaluated for use in healthcare. However, concerns about their impact on disparities persist. This study reviews current research on demographic biases in large language models to identify prevalent bias ...
Mahmud Omar   +10 more
doaj   +1 more source

Data-driven property verification of grey-box systems by Bayesian experiment design

open access: yes, 2015
A measurement-based statistical verification approach is developed for systems with partly unknown dynamics. These grey-box systems are subject to identification experiments which, new in this contribution, enable accepting or rejecting system properties
Haesaert, S.   +6 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Advancements in Multiple Myeloma Research: High-Throughput Sequencing Technologies, Omics, and the Role of Artificial Intelligence

open access: yesBiology
Multiple myeloma is a complex and challenging type of blood cancer that affects plasma cells in the bone marrow. In recent years, the development of advanced research techniques, such as omics approaches—which involve studying large sets of biological ...
Alejandra Gutiérrez-González   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy