Results 141 to 150 of about 19,419,888 (317)
Exploring GPCR signaling pathway networks as cancer therapeutic targets
Cell GenomicsGPCR signaling can contribute to establishing the tumor microenvironment and influence the progression and metabolism of tumors. Arora et al.1 describe a systems-level approach to investigate the patterns of co-expression of GPCR signaling pathway ...
Balaji Santhanam +2 more
doaj +1 more source
Data Driven Design for PSS (Product Re-design Based on Previous Knowledge)
The use of data-driven techniques can support the trade-off between different PSS design concepts by allowing dynamic indexing and retrieval of information to detect correlations and emerging trends. The chapter presents a data-driven approach exploiting
Bertoni, Alessandro,
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
reservedRapid technological developments are redefining what it means to be a data-driven company. Today, organizations are using sporadically Artificial Intelligence (AI) and Business Intelligence (BI) to predict trends and uncover insights, based on ...
BADARAU, ADRIAN
core
Data-Driven Learning and vocabulary teaching: a study on collocations [PDF]
openThis dissertation investigates the integration of Data Driven Learning (DDL) methodology in vocabulary acquisition, with a specific emphasis on collocations.
ZAMPAGLIONE, SIMONA
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
An algorithm for closed-loop data-driven simulation
Closed-loop data-driven simulation refers to the problem of constructing trajectories of a closed-loop system directly from data of the plant and a representation of the controller.
Markovsky, Ivan
core
From Model-based to Data-driven LMI-based Controller Synthesis [PDF]
openThis thesis uses Linear Matrix Inequalities (LMIs) to transition from model-based to data-driven control design, while preserving guarantees with regard to stability and performance of the resulting closed-loop system.
KRASSOWIZKIY, MICHAEL
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source