Results 121 to 130 of about 58,206,617 (356)
Cariboo Amalgamated Gold Mines Limited: [PDF]
, 1933 Cariboo Amalgamated Gold Mines Limited (Non-Personal Liability), owning outright and developing approximately 175 mineral claims in the Barkerville area, Cariboo Mining District, formerly owned by Fred M.
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Bowater Organisation Annual Reports 1949 [PDF]
, 1949 The Bowater Organisation Annual Reports 1949Foreword -- Companies comprising the Bowater Organisation -- Directors and other officials of the Organisation -- Directors' report and accounts of.
Bowater Corporation Limited
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Journal of Contemporary Eastern Asia, 2018 Open Science is an umbrella term that involves various movements aiming to remove the barriers to sharing any kind of output, resources, methods or tools at any stage of the research process.
Sharif, Naubahar +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Fisheries Research, 2019 Use of data-limited methods for setting target catches is increasing in the Northeast U.S., but there remains considerable uncertainty over which methods may be suitable for stocks in the region.
J. Wiedenmann +2 more
semanticscholar +1 more source
A New Rapid Incremental Algorithm for Constructing Concept Lattices
Information, 2019 Formal concept analysis has proven to be a very effective method for data analysis and rule extraction, but how to build formal concept lattices is a difficult and hot topic.
Jingpu Zhang +3 more
doaj +1 more source