Results 131 to 140 of about 58,206,617 (356)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Trends in age at male circumcision and its determinants in Rwanda
Background Voluntary medical male circumcision (VMMC) is a well-established public health intervention proven to reduce the risk of human immunodeficiency virus (HIV) infection.
Theogene Kubahoniyesu +5 more
doaj +1 more source
Estimating uncertainty of data limited stock assessments
Many methods exist to assess the fishing status of data-limited stocks; however, little is known about the accuracy or the uncertainty of such assessments. Here we evaluate a new size-based data-limited stock assessment method by applying it to well-assessed, data-rich fish stocks treated as data-limited.
Alexandros Kokkalis +4 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Experian Demographic Data, 2004-2005 and 2008-2011 [PDF]
copyright UK Data Service and data collection copyright owner.Demographic information specialists Experian Limited have made available a selection of their popular datasets at 2001 Lower Layer Super Output Area (LSOA) level.
Experian Limited
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The objective of the present work is a spatial analysis aimed at supporting hydrological and water quality model applications in the Canale d’Aiedda basin (Puglia, Italy), a data-limited area.
E. D’Ambrosio +16 more
semanticscholar +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
LSHTM Data Compass Statistics Report - 2015 [PDF]
Download figures for LSHTM Data Compass during the repository’s testing phase in May-June 2015 and following its launch in July 2015. Data covers the number of downloads per month, the most downloaded items in the repository, and the most popular authors
Knight, G, Knight, Gareth
core +1 more source

