Results 31 to 40 of about 2,320,360 (265)

Formal Approach to Data Accuracy Evaluation

Informatica, 2022
Usually, data quality is defined by multiple attributes that allow classifying the output data (such as completeness, freshness, and accuracy) or the methods exploiting these data (such as dependability, performance, and protection). Among the suggested quality attributes, we will discuss one of the principal categories: data accuracy.
Belkacem Athamena, Zina Houhamdi
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Accuracy of Data Collected by Surgical Residents [PDF]

Journal of Oral and Maxillofacial Surgery, 2008
Clinician records are the primary information source for assessing the quality of facial injury care, billing, risk management, planning of health services, and health-system management and reporting. Inaccuracies obscure outcomes assessment and affect the planning of health services.
Vivek, Shetty, Debra A, Murphy, Cory, Zigler, Judith, Resell, Dennis Duke, Yamashita   +4 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Definitional Discrepancies: Defining “School Shootings” and Other Incidents of Gunfire Affecting Schools

Social Sciences
The current review explores multiple definitions of school shootings used by myriad data collection platforms and by various scholars. Importantly, the impacts of definitional discrepancies on inclusion criteria, data divergence, research, policy, and ...
Benjamin P. Comer
doaj   +1 more source

A validity and reliability of the atraumatic care education model questionnaire based on family-centred care in minimising the stress of hospitalisation in children [PDF]

Scripta Medica
Background/Aim: Hospitalisation is a traumatic occurrence in which children must be admitted for acute or chronic diseases. The purpose of this study was to test the validity and reliability of the atraumatic care education model test, instrument based ...
Alfiyanti Dera, Sufyanti Arief Yuni, Krisnana Ilya, Triharini Mira, Pranata Satriya   +4 more
doaj   +1 more source