Results 121 to 130 of about 25,895,715 (350)

A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation [PDF]

, 2015
Alexander P. Fields, Edwin H. Rodriguez, Marko Jovanović, Noam Stern‐Ginossar, Brian J. Haas, Philipp Mertins, Raktima Raychowdhury, Nir Hacohen, Steven A. Carr, Nicholas T. Ingolia, Aviv Regev, Jonathan S. Weissman   +11 more
openalex   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Recent novel approaches for population genomics data analysis [PDF]

, 2014
Kimberly R. Andrews, Gordon Luikart
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Fitting Large Factor Analysis Models With Ordinal Data [PDF]

, 2018
Christine DiStefano, Heather L. McDaniel, Liyun Zhang, Dexin Shi, Zhehan Jiang   +4 more
openalex   +1 more source

Analysis of Ultrafast Transient Absorption Spectroscopy Data using Integrative Data Analysis Platform: 1. Data Processing, Fitting, and Model Selection [PDF]

, 2017
This manuscript describes a workflow for analysis of transient absorption (TA) spectroscopy data using Integrative Data Analysis Platforms (IDAP) software package. Time-dependent spectral series are analyzed through evaluation of the isosbestic point and
Kovriguine, Evgueni
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An antimicrobial drug recommender system using MALDI-TOF MS and dual-branch neural networks

eLife
Timely and effective use of antimicrobial drugs can improve patient outcomes, as well as help safeguard against resistance development. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is currently routinely ...
Gaetan De Waele, Gerben Menschaert, Willem Waegeman   +2 more
doaj   +1 more source

Sentiment Analysis on Banking Feedback and News Data using Synonyms and Antonyms [PDF]

, 2023
Aniruddha Mohanty, Ravindranath C. Cherukuri   +1 more
openalex   +1 more source

Statistical topological data analysis using persistence landscapes [PDF]

, 2015
We define a new topological summary for data that we call the persistence landscape. Since this summary lies in a vector space, it is easy to combine with tools from statistics and machine learning, in contrast to the standard topological summaries ...
Bubenik, Peter
core