Results 151 to 160 of about 9,437,828 (334)
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar+4 more
wiley +1 more source
ANALYSIS OF CONDUCTANCE DATA FOR 1-1 IONOPHORES
Raymond M. Fuoss, Filippo Accascina
openalex +1 more source
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy+12 more
wiley +1 more source
Applications of dimensional analysis to spray-nozzle performance data
M.R. Shafer, H.L. Bovey
openalex +1 more source
Ian Gregory: An analysis of familial data on psychiatric patients: parental age, family size, birth order, and ordinal position. From British Journal of Preventive & Social Medicine, Vol. 12, No. 1; 01 1958. [PDF]
Menninger William C.
openalex +1 more source
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen+6 more
wiley +1 more source
The St. Lawrence earthquake, February 28, 1925 (a final analysis of the data collected)
E A Hodgson
openalex +1 more source
A critical examination of the statistical method for the analysis of gas electron diffraction data [PDF]
Yusuke Morino, K. Kuchitsu, Y. Murata
openalex +1 more source