Results 151 to 160 of about 25,895,715 (350)

Unveiling the social fabric through a temporal, nation-scale social network and its characteristics

Scientific Reports
Social networks shape individuals’ lives, influencing everything from career paths to health. This paper presents a registry-based, multi-layer and temporal network of the entire Danish population from 2008 to 2021.
Jolien Cremers, Benjamin Kohler, Benjamin Frank Maier, Stine Nymann Eriksen, Johanna Einsiedler, Frederik Kølby Christensen, Sune Lehmann, David Dreyer Lassen, Laust Hvas Mortensen, Andreas Bjerre-Nielsen   +9 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Metapopulation models with anti-symmetric Lotka–Volterra systems

Journal of Biological Dynamics
We consider different anti-symmetric Lotka–Volterra systems governing the pairwise interactions among the same n species inhabiting m spatially discrete habitat patches, with each patch having infinitely many equilibria.
Anju Susan Anish, Bernard De Baets, Shodhan Rao   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Tweet My Street: A Cross-Disciplinary Collaboration for the Analysis of Local Twitter Data [PDF]

, 2014
G Mearns, Rebecca Simmonds, Ranald Richardson, Mark Turner, Paul Watson, Paolo Missier   +5 more
openalex   +1 more source

Bi-directional emotional contagion: An analysis of chinese parents’ social media data

, 2022
Wenwei Luo, Ilene R. Berson, Michael J. Berson   +2 more
openalex   +1 more source

Analysis of Driver Behavior and Intervehicular Collision: A Data-Based Traffic Modeling and Simulation Approach [PDF]

, 2022
Lu Zhao, Nadir Farhi, Zoi Christoforou, Nadia Haddadou   +3 more
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source