Results 151 to 160 of about 796,452 (265)

Qualitative Data Clustering to Detect Outliers. [PDF]

Entropy (Basel), 2021
Nowak-Brzezińska A, Łazarz W.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Global understanding via local extraction for data clustering and visualization. [PDF]

Patterns (N Y)
Zhang Z, Li B.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Enhanced aquila optimizer for global optimization and data clustering. [PDF]

Sci Rep
Abualigah L, Alomari SA, Almomani MH, Abu Zitar R, Migdady H, Saleem K, Smerat A, Snasel V, Gandomi AH.   +8 more
europepmc   +1 more source

Clustering Deviation Index (CDI): a robust and accurate internal measure for evaluating scRNA-seq data clustering. [PDF]

Genome Biol, 2022
Fang J, Chan C, Owzar K, Wang L, Qin D, Li QJ, Xie J.   +6 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

scRECL: representative ensembles with contrastive learning for scRNA-seq data clustering analysis. [PDF]

Brief Bioinform
Huang Y, Jiang H, Ching WK, Shen D.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Extracting preference relations from data: Clustering with transitive centroids. [PDF]

Behav Res Methods
de Chiusole D, Stefanutti L, Brancaccio A.   +2 more
europepmc   +1 more source