Results 81 to 90 of about 28,374,038 (313)

Bisociative knowledge discovery for microarray data analysis [PDF]

, 2010
Peer ...
Gruden, Kristina, Kulovesi, Kimmo, Lavrac, Nada, Motaln, Helena, Mozetic, Igor, Novak, Petra Kralj, Petek, Marko, Podpecan, Vid, Toivonen, Hannu   +8 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The Smallest Grammar Problem as Constituents Choice and Minimal Grammar Parsing

Algorithms, 2011
The smallest grammar problem—namely, finding a smallest context-free grammar that generates exactly one sequence—is of practical and theoretical importance in fields such as Kolmogorov complexity, data compression and pattern discovery.
Gabriel Infante-Lopez, Rafael Carrascosa, Matthias Gallé, François Coste   +3 more
doaj   +1 more source

Probabilistic Random Forest improves bioactivity predictions close to the classification threshold by taking into account experimental uncertainty

Journal of Cheminformatics, 2021
Measurements of protein–ligand interactions have reproducibility limits due to experimental errors. Any model based on such assays will consequentially have such unavoidable errors influencing their performance which should ideally be factored into ...
Lewis H. Mervin, Maria-Anna Trapotsi, Avid M. Afzal, Ian P. Barrett, Andreas Bender, Ola Engkvist   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Genic constraint against nonsynonymous variation across the mouse genome

BMC Genomics, 2023
Background Selective constraint, the depletion of variation due to negative selection, provides insights into the functional impact of variants and disease mechanisms. However, its characterization in mice, the most commonly used mammalian model, remains
George Powell, Michelle M. Simon, Sara Pulit, Ann-Marie Mallon, Cecilia M. Lindgren   +4 more
doaj   +1 more source

Data-driven PDE discovery with evolutionary approach

, 2019
The data-driven models allow one to define the model structure in cases when a priori information is not sufficient to build other types of models. The possible way to obtain physical interpretation is the data-driven differential equation discovery ...
D Kondrashov, GJ Gray, H Schaeffer, J Berg, J Bongard, S Winkler, SH Rudy   +6 more
core   +1 more source

hddtools: Hydrological Data Discovery Tools

Journal of Open Source Software, 2017
The hddtools (Vitolo 2016) (hydrological data discovery tools) is an R package (R Core Team 2016) designed to facilitate access to a variety of online open data sources relevant for hydrologists and, in general, environmental scientists and practitioners.
C. Vitolo
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Global socioeconomic inequalities in vaccination coverage, supply, and confidence

npj Vaccines
Sustainable Development Goal (SDG) adopted in 2015 aim to reduce inequalities and achieve universal health coverage, including access to essential vaccines for all.
Qiang Wang, Kathy Leung, Mark Jit, Joseph T. Wu, Leesa Lin   +4 more
doaj   +1 more source