Results 91 to 100 of about 3,447,982 (286)
Discovery and Reuse of Open Datasets: An Exploratory Study
Journal of eScience Librarianship, 2016 Objective: This article analyzes twenty cited or downloaded datasets and the repositories that house them, in order to produce insights that can be used by academic libraries to encourage discovery and reuse of research data in institutional repositories.
Sara, Leila, Susan
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Applications of Artificial Intelligence in the IoT
Applied SciencesInternet of Things (IoT) systems face various challenges in real-world applications, including operational, performance and security issues [...]
Ahmad Akbari Azirani, Bijan Raahemi
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The NYU Data Catalog: a modular, flexible infrastructure for data discovery. [PDF]
J Am Med Inform Assoc, 2023 Yee M, Surkis A, Lamb I, Contaxis N.
europepmc +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Editorial: Artificial intelligence for data discovery and reuse in endocrinology and metabolism. [PDF]
Front Endocrinol (Lausanne), 2023 Angione C, Wang H, Burtt N.
europepmc +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Supporting Data Discovery: Comparing Perspectives of Support Specialists and Researchers
Data Science JournalPurpose: Much of the research in data discovery is centered on the users’ viewpoint, frequently overlooking the perspective of those who develop and maintain the discovery infrastructure.
Guangyuan Sun +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Machine learning-predicted chromatin organization landscape across pediatric tumors
Scientific ReportsStructural variants (SVs) are increasingly recognized as important contributors to oncogenesis through their effects on 3D genome folding. Recent advances in whole-genome sequencing have enabled large-scale profiling of SVs across diverse tumors, yet ...
Ketrin Gjoni +8 more
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