Results 61 to 70 of about 1,380,281 (286)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Energy-Aware Matrix Completion-Based Data Gathering Scheme for Wireless Sensor Networks

open access: yesIEEE Access, 2020
In the Wireless Sensor Networks (WSNs), ensuring long-term survival of the sensor devices is crucial, especially for non-energy harvesting networks where the sensors have to deal with the available limited power. Thus, there is a huge need to efficiently
Manel Kortas   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

PRESENT-DAY VIEWS ON ETHICS OF AUTOMATED PEDAGOGICAL DIAGNOSTICS

open access: yesІнформаційні технології і засоби навчання, 2010
Views of education process participants on the ethics of automated pedagogical diagnostics are studied by questioning. Ethics requirements for design of the automated pedagogical diagnostics systems and possibilities of developing the methods of ...
Oleksandr H. Kolhatin
doaj  

GeoIntelligence: Data Mining Locational Social Media Content for Profiling and Information Gathering [PDF]

open access: yes, 2011
The current social media landscape has resulted in a situation where people are encouraged to share a greater amount of information about their day-to-day lives than ever before.
Baatard, Gregory, Hannay, Peter
core   +1 more source

Efficient Data Gathering in Wireless Sensor Networks Based on Matrix Completion and Compressive Sensing

open access: yes, 2013
Gathering data in an energy efficient manner in wireless sensor networks is an important design challenge. In wireless sensor networks, the readings of sensors always exhibit intra-temporal and inter-spatial correlations.
Chen, Lei, Xiong, Jiping, Zhao, Jian
core   +1 more source

A survey of software development practices in the New Zealand software industry [PDF]

open access: yes, 2000
We report on the software development techniques used in the New Zealand software industry, paying particular attention to requirements gathering. We surveyed a selection of software companies with a general questionnaire and then conducted in-depth ...
Groves, Lindsay   +4 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Community-based Data Gathering and Co-management of Marine Resources in Timor-Leste [PDF]

open access: yes, 2013
This the final technical report regarding communication products and outputs created as a result of lessons learned from eleven years of the Fisheries Management Science Programme (FMSP).
John Beddington
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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