Results 71 to 80 of about 1,380,281 (286)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sensors, 2019 This paper proposes a charging-aware multi-mode routing protocol (CMRP) to collect data in the wireless rechargeable sensor networks. The routing mechanism in CMRP is not steady but changes according to the energy charging status of sensors. Sensors that
Shih-Chang Huang
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The revolution in data gathering systems [PDF]
Data acquisition systems used in NASA's wind tunnels from the 1950's through the present time are summarized as a baseline for assessing the impact of minicomputers and microcomputers on data acquisition and data processing.
Cambra, J. M., Trover, W. F.
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
SensorsThis paper presents an energy-efficient and high-accuracy sampling synchronization approach for real-time synchronous data acquisition in wireless sensor networks (saWSNs).
Tadeusz Sondej, Mariusz Bednarczyk
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Focus group, a data gathering method
نشریه پرستاری ایران, 2011 Introduction: Using focus group to collect data is a valuable method for qualitative researchers. This method is being used increasingly in nursing research. It can provide rich information about a special topic through group dynamics.
Sh. Khosravi, Zh. Abed saeedi
doaj
In-the-wild residual data research and privacy [PDF]
, 2016 As the world becomes increasingly dependent on technology, researchers endeavor to understand how technology is used, the impact it has on everyday life and the life-cycle and span of digital information.
Blyth, Andrew +4 more
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