Results 131 to 140 of about 24,536,364 (296)

Measuring the spatial lag effect of Tobler’s First Law of Geography in Earth system predictive learning

open access: yesScientific Reports
Prediction of complex geographical phenomena is central to geoscience, underpinning climate adaptation, disaster risk reduction, and resource management.
Pingting Zhou   +4 more
doaj   +1 more source

Internet of Things on Banking Processes in South Africa: A Systematic Reflection on Innovations, Opportunities and Challenges

open access: yesDigital Business
The Internet of Things (IoT) represents a digital revolution that is defining global connections across sectors and people at a rapid pace. This extension of the internet beyond the electronic world transforms sectors and industries irrespective of their
Paul Kariuki   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Bridging the Digital Disability Divide: Determinants of Internet Use among Visually Impaired Individuals in Thailand

open access: yesDisabilities
This study investigates the sociodemographic and contextual determinants influencing Internet usage among individuals with visual impairments in Thailand, contributing to the literature on the digital disability divide.
Thitiphat Phochai   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Data Governance and Data for Governance – a circular and regulatory perspective on data

open access: yes
This report is part of the Smart Urban Traffic Zones project, which aims to develop intelligent urban solutions to increase flexibility in the use of urban space, optimize transport efficiency, and improve traffic safety. This involves testing and evaluating digital tools such as geofencing, sensors, and digital signage within the city.
Andersson, Kristina, Nordell, Emmie
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Data strategy and policies: The role of data governance in data ecosystems

open access: yes
2755Many companies have already formulated or are currently in the process of formulating a data strategy to establish long-term target systems for the management and the economic exploitation of data.
Gelhaar, Joshua   +2 more
core   +1 more source

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