Results 121 to 130 of about 24,536,364 (296)

REFORMASI BIROKRASI MENUJU GOOD GOVERNANCE

open access: yes, 2020
Globalization in various areas of life , especially the advancement of information technology and the transformation has encouraged the changing needs of the community , as well . encourage governments as public administration and public management to be
Indah, Diani
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Data Governance in Healthcare Organizations

open access: yes
The Next Generation eHealth has a critical data goverance component. In order also to have an effective design and implementation of a robust Data Strategy, a holistic approach to Data governance is requires.
Housawi, Abdulrahman, Lytras, Miltiadis
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Ethics in the Governance of Data and Digital Technology: An Analysis of European Data Regulations and Policies [PDF]

open access: yes
Addressing ethical concerns is among the fundamental motivations for the development of policies and regulations for data and digital technologies.
Stahl, Bernd, Eke, Damian
core   +1 more source

Impact of a Master Data Management Framework to Trigger Data Governance Maturity: A Systematic Literature Review

open access: yesIEEE Access
Data governance plays a crucial role for organizations aiming to improve data quality, security, and compliance, yet research reveals ongoing challenges in implementation, maturity, and the practical effectiveness of current frameworks.
Leonardo Guerreiro   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Building Resilience in Trans-boundary Social-Ecological Systems: Adaptive Governance in the Lake Champlain Richelieu River Basin

open access: yes, 2019
Addressing the management of water bodies that cross political, cultural, and ecological boundaries entails working with a level of complexity that requires creative, adaptive management strategies that build resilience throughout the system and allow ...
Spett, Emma J
core   +1 more source

Assessing the carbon reduction potential of municipal solid waste incineration at the county level in China

open access: yesResources, Environment and Sustainability
Municipal solid waste (MSW) incineration plants play a crucial role both in waste-to-energy sector and “Zero-waste Cities” construction in China. As the number and capacity of waste incineration plants (WIPs) are increasing rapidly, their expansion ...
Fangyi Li   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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