Results 111 to 120 of about 1,429,854 (290)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Internet Use for Health-Related Purposes among Older People in Thailand: An Analysis of Nationwide Cross-Sectional Data

open access: yesInformatics
As the global population ages, understanding the digital health behaviors of older adults becomes increasingly crucial. In Thailand, where the elderly population is rapidly growing, examining how older individuals use the internet for health-related ...
Kittisak Robru   +3 more
doaj   +1 more source

Globalisation, Governance and Economic Growth in West Africa: The Case of Cote D' Ivoire and Nigeria [PDF]

open access: yes, 2007
Globalization conveys varying messages to its audience due to its trans-disciplinary nature, and the pattern of governance and socio-political atmosphere in a given economy can influence the e),.1entto which globalization is harnessed.
Osabuohien, E. S. C.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Corporate Governance and Market Valuation in China [PDF]

open access: yes
This paper studies the relationship between the governance mechanisms and the market valuation of publicly listed firms in China empirically. We construct measures for corporate governance mechanisms and measures of market valuation for all publicly ...
Chong-En Bai   +4 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The need for climate data stewardship: 10 tensions and reflections regarding climate data governance

open access: yesData & Policy
Datafication—the increase in data generation and advancements in data analysis—offers new possibilities for governing and tackling worldwide challenges such as climate change.
Stefaan G. Verhulst
doaj   +1 more source

THE INFLUENCE OF ENVIRONMENTAL, SOCIAL AND GOVERNANCE (ESG) DISCLOSURE ON FIRM RISK (Empirical Study on Non-Financial Companies Listed in Indonesia Stock Exchange) [PDF]

open access: yes, 2018
This study aims to analyze the influence of Environmental, Social and Governance (ESG) disclosure on firm risk. ESG disclosure covers the environmental, social and governance issues considered by stakeholders to reflect a company’s accountability.
ARITONANG, Fitri Anita, HARTO, Puji
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Bridging the Digital Disability Divide: Determinants of Internet Use among Visually Impaired Individuals in Thailand

open access: yesDisabilities
This study investigates the sociodemographic and contextual determinants influencing Internet usage among individuals with visual impairments in Thailand, contributing to the literature on the digital disability divide.
Thitiphat Phochai   +3 more
doaj   +1 more source

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