Results 91 to 100 of about 1,429,854 (290)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Good Governance Indicators of the Millennium Challenge Account: How many dimensions are really being measured [PDF]
This paper assesses the validity of the perception-based governance indicators used by the US Millennium Challenge Account (MCA) for aid allocation decisions.
Knoll, Martin, Zloczysti, Petra
core +3 more sources
Does Governance Matter?Some Evidence from Indian States [PDF]
This paper attempts to propose a methodology to combine different dimensions of governance indicators into a composite index. The governance index is computed as the weighted average of principal components of the standardized governance indicators ...
Sudip Ranjan Basu
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Big Data Dynamic Aggregation and Intelligent Service Model for Multimodal Healthcare and Eldercare [PDF]
Nongye tushu qingbao xuebao[Purpose/Significance] Against the backdrop of an accelerating population aging trend, the integration of big data and intelligent services in multimodal healthcare and eldercare has become pivotal for enhancing the quality of medical and eldercare ...
YANG Xuejie, LIU Jia, WU Qingxiao, WANG Yufei, GU Dongxiao
doaj +1 more source
Regulatory governance and sector performance : methodology and evaluation for Electricity distribution in Latin America [PDF]
This paper contributes to the literature that explores the link between regulatory governance and sector performance. The paper develops an index of regulatory governance and estimates its impact on sector performance, showing that indeed regulation and ...
Andres, Luis +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
IEEE AccessData governance plays a crucial role for organizations aiming to improve data quality, security, and compliance, yet research reveals ongoing challenges in implementation, maturity, and the practical effectiveness of current frameworks.
Leonardo Guerreiro +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Resources, Environment and SustainabilityMunicipal solid waste (MSW) incineration plants play a crucial role both in waste-to-energy sector and “Zero-waste Cities” construction in China. As the number and capacity of waste incineration plants (WIPs) are increasing rapidly, their expansion ...
Fangyi Li +4 more
doaj +1 more source