Results 81 to 90 of about 158,842 (252)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Spectral–Spatial Hypergraph Convolutional Network for Hyperspectral Image Classification

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In recent years, due to the high-order nonlinear modeling capability of hypergraph convolutional network (HGCN), it has been introduced into the field of hyperspectral image (HSI) classification.
Qingwang Wang, Fenlian Liu, Mingguo Wang, Lizhi Wang, Jiangbo Huang, Tao Shen   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Big Data Dynamic Aggregation and Intelligent Service Model for Multimodal Healthcare and Eldercare [PDF]

Nongye tushu qingbao xuebao
[Purpose/Significance] Against the backdrop of an accelerating population aging trend, the integration of big data and intelligent services in multimodal healthcare and eldercare has become pivotal for enhancing the quality of medical and eldercare ...
YANG Xuejie, LIU Jia, WU Qingxiao, WANG Yufei, GU Dongxiao
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Impact of a Master Data Management Framework to Trigger Data Governance Maturity: A Systematic Literature Review

IEEE Access
Data governance plays a crucial role for organizations aiming to improve data quality, security, and compliance, yet research reveals ongoing challenges in implementation, maturity, and the practical effectiveness of current frameworks.
Leonardo Guerreiro, Jose Martins, Maria do Rosario Bernardo, Henrique Mamede, Frederico Branco   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Assessing the carbon reduction potential of municipal solid waste incineration at the county level in China

Resources, Environment and Sustainability
Municipal solid waste (MSW) incineration plants play a crucial role both in waste-to-energy sector and “Zero-waste Cities” construction in China. As the number and capacity of waste incineration plants (WIPs) are increasing rapidly, their expansion ...
Fangyi Li, Qi Zhang, Wu Xie, Zhen Shao, Jingjing Li   +4 more
doaj   +1 more source