Results 111 to 120 of about 4,439,564 (294)

Clinically acquired new challenging dataset for brain SOL segmentation: AJBDS-2023

Data in Brief
Space-occupying lesions (SOL) brain detected on brain MRI are benign and malignant tumors. Several brain tumor segmentation algorithms have been developed but there is a need for a clinically acquired dataset that is used for real-time images.
Javaria Amin, Muhammad Almas Anjum, Nadia Gul, Muhammad Sharif, Seifedine Kadry   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Data on LC–MS profile of Brucea javanica (L.) Merr. and the NMR data of its major indole alkaloids

Data in Brief
This article presents two types of phytochemical data obtained from Brucea javanica (L.) Merr. roots, a medicinal plant belonging to the Simaroubaceae family.
Nor Syaidatul Akmal Mohd Yousof, Norazlan Mohmad Misnan, Akmal Hayat Abdul Karim, Murizal Zainol, Mohd Ridzuan Mohd Abd Razak, Nur Hana Md Jelas, Nor Hadiani Ismail, Adlin Afzan   +7 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Dataset from the uniaxial tensile testing of human curly hair fibers under different conditions

Data in Brief
Individual human hair fibers exhibiting a curly morphology were procured from a female donor within her early thirties (30s). The selected hair fibers donor had refrained from undergoing any form of chemical treatment, including dyeing, relaxing, and ...
Lebogang Mathebela, Rudzani Sigwadi, Tetelo Lekwana, Harry Ngwangwa, Thanyani Pandelani, Fulufhelo Nemavhola   +5 more
doaj   +1 more source

Intermittency and the passive nature of the magnitude of the magnetic field

, 2004
It is shown that the statistical properties of the magnitude of the magnetic field in turbulent electrically conducting media resemble, in the inertial range, those of passive scalars in fully developed three-dimensional fluid turbulence. This conclusion,
A. Barnes, A. Barnes, A. Bershadskii, A. S. Monin, H. K. Moffatt, J. W. Belcher, K. R. Sreenivasan, L. F. Burlaga, M. L. Goldstein, M. L. Goldstein, S. Oughton, T. Watanabe, Ya. B. Zeldovich   +12 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

TLFS23 Tamil language fingerspelling dataset

Data in Brief
Tamil is one of the oldest existing languages, spoken by around 65 million people across India, Sri Lanka and South-East Asia. Countries such as Fiji and South Africa also have a significant population with Tamil ancestry. Tamil is a complex language and
Bavesh Ram S, Chirranjeavi M, Aaruran S, Gokulraj VA, Binoy B Nair, Harikumar M．E   +5 more
doaj   +1 more source

Real-world data: a brief review of the methods, applications, challenges and opportunities. [PDF]

BMC Med Res Methodol, 2022
Liu F, Panagiotakos D.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source