Results 121 to 130 of about 4,439,564 (294)

DbKB a knowledge graph dataset for diabetes: A system biology approach

Data in Brief
Diabetes has emerged as a prevalent disease, affecting millions of individuals annually according to statistics. Numerous studies have delved into identifying key genes implicated in the causal mechanisms of diabetes. This paper specifically concentrates
Rauf Ahmed Shams Malick, Siraj Munir, Syed Imran Jami, Shoaib Rauf, Stefano Ferretti, Hocine Cherifi   +5 more
doaj   +1 more source

Corrigendum to "Experimental dataset on the compressive mechanical properties of high-density pressboard used in power transformers spacers" [Data in Brief 50 (2023) 109471]. [PDF]

Data Brief, 2023
Oria C, Carrascal I, Ferreño D, Méndez C, Ortiz A.   +4 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The dataset of duplex ultrasound assessment of the internal mammary artery in women with unilateral mastectomy followed by radiotherapy for breast cancer

Data in Brief
Adjuvant radiotherapy for breast cancer may involve some incidental exposure of the ipsilateral internal mammary artery to ionizing radiation. However, the relevant evidence is limited and inconsistent.
Thanh-Phong Le, Anh T. Le, Tan N.D. Huynh, Thu-Ha Dao, Pascal Desgranges, Romain Bosc   +5 more
doaj   +1 more source

Corrigendum to: Draft genome sequence dataset of Latilactobacillus curvatus PN39MY isolated from fermented vegetables Data in Brief, 49 (2023) 109436. [PDF]

Data Brief, 2023
Daliri EB, Balnionytė T, Lastauskienė E, Burokas A.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Dataset of clinical cases, images, image labels and captions from open access case reports from PubMed Central (1990–2023)

Data in Brief
This paper details the acquisition, structure and preprocessing of the MultiCaRe Dataset, a multimodal case report dataset which contains data from 75,382 open access PubMed Central articles spanning the period from 1990 to 2023.
Mauro Andrés Nievas Offidani, Claudio Augusto Delrieux   +1 more
doaj   +1 more source

Corrigendum to "acoustic dataset of coconut (cocos nucifera) based on tapping system" [Data in Brief, Volume 47, April 2023, 108936]. [PDF]

Data Brief, 2023
Caladcad JA, Piedad EJ.
europepmc   +1 more source

Declining Childhood Obesity Rates - Where Are We Seeing Signs of Progress? [PDF]

, 2013
In recent years, the national childhood obesity rate has leveled off. However, reports from across the country confirm that childhood obesity rates have declined in some cities, counties, and states.

core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source