Results 91 to 100 of about 28,602,314 (397)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Data-Interpretation Methodologies for Non-Linear Earthquake Response Predictions of Damaged Structures

Frontiers in Built Environment, 2017
Seismic exposure of buildings presents difficult engineering challenges. The principles of seismic design involve structures that sustain damage and still protect inhabitants.
Y. Reuland, P. Lestuzzi, I. Smith
semanticscholar   +1 more source

The interpretation of complementation data

Genetical Research, 1966
The evidence for complementation maps being linear is examined by analysis of all known complementation maps in micro-organisms, and by constructing maps from mutants randomly sampled from amongst those at theleu-2locus inNeurosporawith known complementing properties.
openaire   +3 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Teaching Real Data Interpretation with Models (TRIM): Analysis of Student Dialogue in a Large-Enrollment Cell and Developmental Biology Course

CBE - Life Sciences Education, 2016
Data interpretation is an important skill that should be developed within undergraduate biology courses. The authors present instruction in which students collaborate to understand authentic data using biological models.
Patricia Zagallo, Shanice Meddleton, M. Bolger   +2 more
semanticscholar   +1 more source

Verifying Accuracy of Data Registration in Households\' Files Living in Rural Areas of Hamadan County in 2011

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: Initial information is necessary for decision and policy making. A weak information system leads to poor decision-making but the accuracy of data registration and collection can be a valid supporter for assessing health system ...
Alireza Soltanian, Naser Fayyazi, Farah Khodakarami, Mahdi Maleki   +3 more
doaj  

Axion interpretation of the PVLAS data?

, 2005
The PVLAS collaboration has recently reported the observation of a rotation of the polarization plane of light propagating through a transverse static magnetic field.
Andreas Ringwald, Duvillaret L, Jaeckel J, Kleban M, Masso E, Rabadan R, Raffelt G, Zavattini E [PVLAS Collaboration], Zhitnitsky A   +8 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

On the Genetic Interpretation of Disease Data

PLoS ONE, 2010
The understanding of host genetic variation in disease resistance increasingly requires the use of field data to obtain sufficient numbers of phenotypes. We introduce concepts necessary for a genetic interpretation of field disease data, for diseases caused by microparasites such as bacteria or viruses. Our focus is on variance component estimation and
Bishop, Stephen C., Woolliams, John A.
openaire   +6 more sources

Interpretation of altimeter data [PDF]

Two methods are used to interpret the whole range of signals contained in the Geos 3 altimeter data. They each address a different class of events and thus complement each other in their ability to provide information on the state of convection in the ...
Roufosse, M. C.
core   +1 more source