Results 101 to 110 of about 6,412,077 (299)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Orbit IMU alinement interpretation of onboard display data [PDF]

open access: yes
The space shuttle inertial measurement unit (IMU) alinement algorith was examined to determine the most important alinement starpair selection criterion. Three crew displayed parameters were considered: (1) the results of the separation angle difference
Corson, R.
core   +1 more source

Geostatistical interpretation of paleoceanographic data over large ocean basins - Reality and fiction [PDF]

open access: yes, 1998
A promising approach to reconstruct oceanographic scenarios of past time slices is to drive numerical ocean circulation models with sea surface temperatures, salinities, and ice distributions derived from sediment core data.
Hervada-Sala, C.   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Machine Learning-Based Objective Evaluation Model of CTPA Image Quality: A Multi-Center Study

open access: yesInternational Journal of General Medicine
Qihang Sun,1 Zhongxiao Liu,1 Tao Ding,1 Changzhou Shi,2 Nailong Hou,2 Cunjie Sun1 1Department of Medical Imaging, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of China; 2School of Medical Imaging, Xuzhou Medical ...
Sun Q   +5 more
doaj  

THE BIVARIATE CORRELATION COEFFICIENT: FROM CONCEPT TO APPLICATION

open access: yesCentral Asian Journal of Medical Hypotheses and Ethics
The bivariate correlation coefficient is among the most fundamental and widely applied measures in statistical analysis, offering a quantitative assessment of the association between two continuous variables.
Farrokh Habibzadeh
doaj   +1 more source

Software for InterCriteria Analysis results visualization in the intuitionistic fuzzy triangle: Opportunities for data interpretation [PDF]

open access: yesNotes on IFS
In the current investigation a program implementation for data visualization into the intuitionistic fuzzy triangle according to the InterCriteria analysis notation is discussed. The presented software provides an opportunity for in-depth analysis of the
Miroslav Genov, Veselina Bureva
doaj   +1 more source

Infrared spectroscopy for geologic interpretation of TIMS data [PDF]

open access: yes
The Portable Field Emission Spectrometer (PFES) was designed to collect meaningful spectra in the field under climatic, thermal, and sky conditions that approximate those at the time of the overflight.
Bartholomew, Mary Jane
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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