Results 111 to 120 of about 2,823,109 (311)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

THE BIVARIATE CORRELATION COEFFICIENT: FROM CONCEPT TO APPLICATION

Central Asian Journal of Medical Hypotheses and Ethics
The bivariate correlation coefficient is among the most fundamental and widely applied measures in statistical analysis, offering a quantitative assessment of the association between two continuous variables.
Farrokh Habibzadeh
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Machine Learning-Based Objective Evaluation Model of CTPA Image Quality: A Multi-Center Study

International Journal of General Medicine
Qihang Sun,1 Zhongxiao Liu,1 Tao Ding,1 Changzhou Shi,2 Nailong Hou,2 Cunjie Sun1 1Department of Medical Imaging, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, People’s Republic of China; 2School of Medical Imaging, Xuzhou Medical ...
Sun Q, Liu Z, Ding T, Shi C, Hou N, Sun C   +5 more
doaj  

Software for InterCriteria Analysis results visualization in the intuitionistic fuzzy triangle: Opportunities for data interpretation [PDF]

Notes on IFS
In the current investigation a program implementation for data visualization into the intuitionistic fuzzy triangle according to the InterCriteria analysis notation is discussed. The presented software provides an opportunity for in-depth analysis of the
Miroslav Genov, Veselina Bureva
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Semantic Image Interpretation - Integration of Numerical Data and Logical Knowledge for Cognitive Vision [PDF]

, 2018
Semantic Image Interpretation (SII) is the process of generating a structured description of the content of an input image. This description is encoded as a labelled direct graph where nodes correspond to objects in the image and edges to semantic ...
Donadello, Ivan, ivan donadello
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Making sense of shaky data in humanitarian crises

Frontiers in Public Health
Humanitarian decision-making occurs in volatile and politically charged environments where information is often incomplete, outdated, or conflicting. Effective humanitarian response often requires interpreting poor-quality data to guide interventions ...
Sandro Colombo, Chiara Altare, Chiara Altare   +2 more
doaj   +1 more source