Results 111 to 120 of about 6,370,482 (358)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Possibilities of the Practical Application of Remote Sensing Data in Real Property Appraisal

Real Estate Management and Valuation, 2015
In the process of real estate evaluation, there are many important elements that should be taken into consideration: for example the type of property which is under evaluation, real estate market analysis, and the selection of appropriate evaluation ...
Dąbrowski Rafał, Latos Dorota
doaj   +1 more source

Common pitfalls in statistical analysis: The perils of multiple testing

Perspectives in Clinical Research, 2016
Multiple testing refers to situations where a dataset is subjected to statistical testing multiple times - either at multiple time-points or through multiple subgroups or for multiple end-points. This amplifies the probability of a false-positive finding.
Priya Ranganathan, C S Pramesh, Marc Buyse   +2 more
doaj   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

Geophysical interpretation of Venus gravity data [PDF]

The investigation of the subsurface mass distribution of Venus through the analysis of the data from Pioneer Venus Orbiter (PVO) is presented. The Doppler tracking data was used to map the gravitational potential, which was compared to the topographic ...
Reasenberg, R. D.
core   +1 more source

Spectral plots and the representation and interpretation of biological data

, 2007
It is basic question in biology and other fields to identify the char- acteristic properties that on one hand are shared by structures from a particular realm, like gene regulation, protein-protein interaction or neu- ral networks or foodwebs, and that ...
A Wagner, A-L Barabási, Anirban Banerjee, B Bolobás, B Bolobás, C Godsil, DJ Watts, F Chung, FM Atay, FM Atay, H Jeong, H Simon, J Jost, J Jost, JG White, Jürgen Jost, KH Wolfe, M Ipsen, M Newman, P Erdős, R Albert, R Merris, R Milo, S Ohno, SN Dorogovtsev, SS Shen-Orr   +25 more
core   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Interpretable Deep Convolutional Neural Networks via Meta-learning [PDF]

arXiv, 2018
Model interpretability is a requirement in many applications in which crucial decisions are made by users relying on a model's outputs. The recent movement for "algorithmic fairness" also stipulates explainability, and therefore interpretability of learning models.
arxiv  

Actionable Interpretation of Machine Learning Models for Sequential Data: Dementia-related Agitation Use Case [PDF]

arXiv, 2020
Machine learning has shown successes for complex learning problems in which data/parameters can be multidimensional and too complex for a first-principles based analysis. Some applications that utilize machine learning require human interpretability, not just to understand a particular result (classification, detection, etc.) but also for humans to ...
arxiv