Results 111 to 120 of about 5,937,551 (333)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Assessment for Learning in K-12 Science Departments: A Case Study

open access: yesJournal of MultiDisciplinary Evaluation, 2009
This paper discusses the efforts of science departments in two secondary schools to implement data-driven decision making at the department level.
William Glenn
doaj   +1 more source

Scalar dark matter interpretation of the DAMPE data with U(1) gauge interactions

open access: yes, 2018
Recently, DAMPE experiment released the new measurement of the total cosmic $e^+e^-$ flux between 25 GeV and 4.6 TeV which indicates a spectral softening at around 0.9 TeV and a tentative peak at around 1.4 TeV.
Cao, Junjie   +5 more
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Infrared spectroscopy for geologic interpretation of TIMS data [PDF]

open access: yes
The Portable Field Emission Spectrometer (PFES) was designed to collect meaningful spectra in the field under climatic, thermal, and sky conditions that approximate those at the time of the overflight.
Bartholomew, Mary Jane
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Orbit IMU alinement interpretation of onboard display data [PDF]

open access: yes
The space shuttle inertial measurement unit (IMU) alinement algorith was examined to determine the most important alinement starpair selection criterion. Three crew displayed parameters were considered: (1) the results of the separation angle difference
Corson, R.
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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