Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Bridging neuromorphic computing and deep learning for next-generation neural data interpretation. [PDF]
Zhang M, Wang T, Zhu Z.
europepmc +1 more source
Human in vivo medial gastrocnemius gear during active and passive muscle lengthening: effect of inconsistent methods and nomenclature on data interpretation. [PDF]
Pinto MD +3 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
An explainable deep learning framework for biosensing data interpretation in biomedical engineering and real-time health diagnostics. [PDF]
Yang Z, Huang W, Zhang H.
europepmc +1 more source
Assay-related differences in SuPAR levels: implications for measurement and data interpretation. [PDF]
Vasbinder A +7 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
"Preoperative Central Sensitization in Pilon Fracture Outcomes: Considerations on Grouping, Analgesia, and Data Interpretation" [Response to Letter]. [PDF]
Liang J +8 more
europepmc +1 more source

