Results 121 to 130 of about 3,128,226 (276)

D3.3 : Mid term revision of the data management plan [PDF]

open access: yes, 2016
The Data Management Plan (DMP) will be reviewed as requested in http://ec.europa.eu/research/participants/data/ref/h2020/grants_manual/hi/oa_pilot/h2020-hi-oa-data-mgt_en.pdf. The review will be conducted in collaboration with WP1 and WP5.
ConnectinGEO   +5 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Baltic Gender Data Management Plan : Version 2 [PDF]

open access: yes, 2017
Provides a summary of the Data Management Plan (DMP) addressing FAIR (findable, accessible, interoperable, re-usable) data, allocation of resources, data security and ethical ...
Kisakurek, Basak   +2 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Integrating automated support for a software management cycle into the TAME system [PDF]

open access: yes, 1989
Software managers are interested in the quantitative management of software quality, cost and progress. An integrated software management methodology, which can be applied throughout the software life cycle for any number purposes, is required. The TAME (
Basili, Victor R., Sunazuka, Toshihiko
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Mapping Research Data at the University of Bologna

open access: yesData Science Journal
This article presents an analysis of research data management (RDM) practices at the University of Bologna (UniBO). It is based on qualitative data manually collected from 29 data management plans (DMPs) and recorded within a table based on 27 relevant ...
Chiara Basalti   +6 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

madmpy: A Python library for creating and validating Data Management Plans

open access: yesSoftwareX
Data Management Plans (DMPs) are documents that describe the data used and produced during the course of research projects. Machine-actionable DMPs (maDMPs) are plans written in computer-readable formats.
Alberto Ballesteros-Rodríguez   +2 more
doaj   +1 more source

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