Results 101 to 110 of about 32,290,400 (291)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Mapping Research Data at the University of Bologna
Data Science JournalThis article presents an analysis of research data management (RDM) practices at the University of Bologna (UniBO). It is based on qualitative data manually collected from 29 data management plans (DMPs) and recorded within a table based on 27 relevant ...
Chiara Basalti +6 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Boulder Creek Critical Zone Observatory Data Management Plan [PDF]
Research Ideas and Outcomes, 2016 Jeri Fey, Suzanne Anderson
doaj +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Master Data Management Plan [PDF]
This Master Data Management Plan (MDMP) defines the strategy for managing the digital final deliverables produced by the Collaborative Sciences Center for Road Safety (CSCRS), a National University Transportation Center funded by the U.S.
University of North Carolina at Chapel Hill
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Exploring the Use of Data in a Digital Twin for the Marine and Coastal Environment
ISPRS International Journal of Geo-InformationThe ocean plays a vital role in our society and represents a constantly changing landscape that is not well understood and therefore needs continuous monitoring and research. Sustainable monitoring is essential to assess both the current and future state
Shelley Haupt +4 more
doaj +1 more source
Data Management and Sharing Plan for: TBD
The Data Management and Sharing Plan describes the scientific data to be generated and/or used in the research and outlines a strategy for managing and sharing project ...
Roth, Bryan
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source