Results 121 to 130 of about 32,290,400 (291)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Essential Aspects of Tools for Developing Scientific Data Management Plans

Data Science Journal
Data Management Plans (DMPs) are relevant documents that help ensure data integrity and transparency. In this study, we analyze tools for constructing DMPs based on the fundamental aspects needed for proper scientific data management.
Fabiano Couto Corrêa Silva, Sandra de Albuquerque Siebra, Laura Vilela Rodrigues Rezende, Alexandre Faria de Oliveira, Denise Oliveira de Araújo   +4 more
doaj   +1 more source

Data Management Plan

, 2019
Project Deliverable D9.1 (V3.0)
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Correction: Essential Aspects of Tools for Developing Scientific Data Management Plans

Data Science Journal
This article details a correction to: Silva, F.C.C., de Albuquerque Siebra, S., Rezende, L.V.R., de Oliveira, A.F. and de Araújo, D.O. (2026) ‘Essential Aspects of Tools for Developing Scientific Data Management Plans’, Data Science Journal, 25(1 ...
Fabiano Couto Corrêa Silva, Sandra de Albuquerque Siebra, Laura Vilela Rodrigues Rezende, Alexandre Faria de Oliveira, Denise Oliveira de Araújo   +4 more
doaj   +1 more source

SMARTER Center Data Management Plan [PDF]

69A3552348303The Sustainable Mobility and Accessibility Regional Transportation Equity Research (SMARTER) Center, led by Morgan State University, collects a wide range of data from testing facilities at its associated universities.
Morgan State University. Sustainable Mobility and Accessibility Regional Transportation Equity Research Center (SMARTER) Region 3 University Transportation Center (UTC), Niehaus, Joseph   +1 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

madmpy: A Python library for creating and validating Data Management Plans

SoftwareX
Data Management Plans (DMPs) are documents that describe the data used and produced during the course of research projects. Machine-actionable DMPs (maDMPs) are plans written in computer-readable formats.
Alberto Ballesteros-Rodríguez, Miguel-Ángel Sicilia, Elena García-Barriocanal   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

SNSF Data Management Plan - EPFL Library template [PDF]

Annotated Data Management Plan template with EPFL recommendations for projects to be submitted to the Swiss National Science Foundation (SNSF).VPA-SISBVPA ...
EPFL Library Research Data Team
core