Results 131 to 140 of about 22,484,217 (350)

Data Mining Concepts and Techniques

open access: yes, 2010
S. Gnanapriya   +3 more
semanticscholar   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

open access: yesAdvanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li   +9 more
wiley   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

Deformation Prediction of 4D‐Printed Active Composite Structures Based on Data Mining

open access: yesAdvanced Science, EarlyView.
A curvature‐driven sequence point generation (CSPG) algorithm based on data mining is proposed to predict the deformation of double‐layer voxelized composite structures of arbitrary lengths. In addition, the CSPG algorithm is applied to predict the deformation of 2D and 3D structures assembled from beam elements, and its effectiveness is validated ...
Mengtao Wang   +6 more
wiley   +1 more source

Durable Thin‐Film Porous Transport Electrodes for High Current Density PEM Water Electrolysis

open access: yesAdvanced Science, EarlyView.
Water electrolysis using porous transport electrodes with sputter‐deposited, ionomer‐free thin films of rutile IrO2 catalyst suppresses Ir dissolution by >10x over other forms of IrOx. The rutile IrO2 catalyst prepared by this readily scalable electrode synthesis method provides stable cell operation at 3 A cm−2 while using low Ir loading (0.4 mg Ir cm−
James L. Young   +18 more
wiley   +1 more source

Enhancing Binding by Electron Transfer at Heterointerfaces of Biochar‐Modified Hydrogel to Improve Utilization Efficiency of Wastewater Recovered Nutrients

open access: yesAdvanced Science, EarlyView.
Enhancing the utilization efficiency of nutrients recovered from wastewater is achieved through hydrogel modification by biochar. The strategy improves nutrient binding to hydrogels via electron transfer at heterointerfaces, thereby reducing nutrient release rate.
Hao Hu   +7 more
wiley   +1 more source

A Modular Biosensor Platform for the Detection of Plastic Monomers and the Engineering of Promiscuous Amidases Toward Challenging Substrates

open access: yesAdvanced Science, EarlyView.
A luciferase is used as biosensor for aldehydes, produced enzymatically from different monomeric building blocks of plastics like polyurethanes (PUs). The screening platform is used to monitor esterase, amidase, and urethanase activity and to guide the selection of enzyme variants with improved hydrolytic activities toward difficult to hydrolyze ...
Ina Somvilla   +12 more
wiley   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

open access: yesAdvanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang   +3 more
wiley   +1 more source

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