Results 41 to 50 of about 23,785,135 (371)
Radiogenomic-based prediction of genetic alterations in oncogenic signaling pathways in lung cancer
Rationale and objectives Lung adenocarcinoma, a type of non-small cell lung cancer (NSCLC), originates from the peripheral lung tissue and is the most prevalent histologic subtype, constituting around 40% of cases.
Priyadharshini Jayachandran +2 more
doaj +1 more source
A comprehensive evaluation of module detection methods for gene expression data
Modules composed of groups of genes with similar expression profiles tend to be functionally related and co-regulated. Here, Saelens et al evaluate the performance of 42 computational methods and provide practical guidelines for module detection in gene ...
Wouter Saelens +2 more
doaj +1 more source
Efficient Analysis of Pattern and Association Rule Mining Approaches
The process of data mining produces various patterns from a given data source. The most recognized data mining tasks are the process of discovering frequent itemsets, frequent sequential patterns, frequent sequential rules and frequent association rules.
Lazzez, Amor, Slimani, Thabet
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Landform recognition is one of the most significant aspects of geomorphology research, which is the essential tool for landform classification and understanding geomorphological processes.
Siwei Lin, Nan Chen, Zhuowen He
doaj +1 more source
Background Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of urate (FEUA) also modulates this response and relates to oxypurinol concentrations. We further evaluated its potential influence
Pascal Richette +13 more
wiley +1 more source
Background Clustered regularly interspaced short palindromic repeats —CRISPR‐associated protein 9 (CRISPR/Cas9) is a gene editing technology that can deliver highly precise genome editing.
Pavithra Nagendran +2 more
doaj +1 more source
Objective We evaluated the role of 25‐hydroxy vitamin D, prednisone and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25‐hydroxy vitamin D [25(OH)D] levels and other potential risk factors with BMD measures (spine T‐scores) and osteoporosis ...
Nima Madanchi +4 more
wiley +1 more source
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase (MMP)‐7, and serum anti‐malondialdehyde‐acetaldehyde (anti‐MAA) antibody for RA‐associated interstitial lung disease risk stratification. Methods Using a multicenter cohort of US veterans with RA, we performed a cross‐
Kelsey Coziahr +16 more
wiley +1 more source
A machine-learning-based hardware-Trojan detection approach for chips in the Internet of Things
With the development of the Internet of Things, smart devices are widely used. Hardware security is one key issue in the security of the Internet of Things.
Chen Dong +3 more
doaj +1 more source

