Results 41 to 50 of about 459,037 (316)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A machine-learning-based hardware-Trojan detection approach for chips in the Internet of Things

International Journal of Distributed Sensor Networks, 2019
With the development of the Internet of Things, smart devices are widely used. Hardware security is one key issue in the security of the Internet of Things.
Chen Dong, Jinghui Chen, Wenzhong Guo, Jian Zou   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Advancing brain tumor diagnosis: Deep siamese convolutional neural network as a superior model for MRI classification

Brain-X
The timely detection and precise classification of brain tumors using techniques such as magnetic resonance imaging (MRI) are imperative for optimizing treatment strategies and improving patient outcomes.
Gowtham Murugesan, Pavithra Nagendran, Jeyakumar Natarajan   +2 more
doaj   +1 more source

Application Of Data Mining

, 2014
Knowledge and understanding of a problem is always the first step in identifying effective solutions.The application of data mining techniques on official data has great potential in supporting goodpublic policy. It is not straight forward and requires a
Singh, Prempratap; CSE department , Unique College Bhopal, Gosawi, Gouri; CSE department , Unique College Bhopal, Dubey, Sulakshana; CSE department , Unique College Bhopal   +2 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Incremental Road Network Update Method with Trajectory Data and UAV Remote Sensing Imagery

ISPRS International Journal of Geo-Information, 2022
GPS trajectory and remote sensing data are crucial for updating urban road networks because they contain critical spatial and temporal information.
Jianxin Qin, Wenjie Yang, Tao Wu, Bin He, Longgang Xiang   +4 more
doaj   +1 more source

Distributed classification for pocket data mining

, 2011
Distributed and collaborative data stream mining in a mobile computing environment is referred to as Pocket Data Mining PDM. Large amounts of available data streams to which smart phones can subscribe to or sense, coupled with the increasing ...
Philip S. Yu, Liu, Han, Bramer, M., Mohamed Medhat Gaber, Max Bramer, Gaber, M., Han Liu, Yu, P., Frederic Stahl, Yu, P. S., Stahl, F., Stahl, Frederic, Bramer, Max, Gaber, M. M., Liu, H.   +14 more
core   +1 more source

Web + Data Mining = Web Mining [PDF]

HMD Praxis der Wirtschaftsinformatik, 2009
Dieser Beitrag gibt eine kurze Beschreibung, was unter dem Begriff Web Mining zu verstehen ist und wie Webdaten mit gangigen Data-Mining-Techniken kombiniert werden konnen, um das Web besser als Informationsquelle nutzbar zu machen. Des Weiteren wird ein Uberblick uber die gangigen Hauptachsen gegeben, entlang derer die meisten aktuellen Entwicklungen ...
openaire   +1 more source