Results 61 to 70 of about 243,501 (262)

Machine Learning‐Informed Nano Co‐Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue

Advanced Materials, EarlyView.
We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu, Qiang Long, Yihao Liu, Xiuqiao Sun, Baoding Zhang, Binxin Liao, Weibin Wu, Wangxi Hai, Pei Zhang, Wenhua Lian, Yuewen Zhu, Zheng Wang, Caisheng Wu, Xianming Deng, Hélder A. Santos, Xiaofeng Ye   +15 more
wiley   +1 more source

Assessing nighttime artificial light pollution from the perspective of an unmanned aerial vehicle tilt

Geocarto International
Increasing artificial light at night (ALAN) impacts urban sustainability and contributes to light pollution. Nighttime satellites miss side ALAN, so drone-captured tilted images and measured illuminance are used to assess ALAN pollution within urban ...
Jiejie Wu, Liang Zhou, Deping Li, Daoquan Zhang, Tingting Jiang, Chengzhi Zong   +5 more
doaj   +1 more source

An Improved HMM-Based Approach for Planning Individual Routes Using Crowd Sourcing Spatiotemporal Data

Sensors, 2020
With the rapid development of LBSs (location-based services) in recent years, researchers have increasingly taken an interest in trying to make travel routes more practicable and individualized.
Tao Wu, Zhixuan Zeng, Jianxin Qin, Longgang Xiang, Yiliang Wan   +4 more
doaj   +1 more source

Bulk and Surface Dual‐Modification for Stabilizing RuO2 Anode in 2 A cm−2 PEMWE Operation

Advanced Materials, EarlyView.
The high‐current‐density stability of the RuO2‐based anode in PEMWE could be taken care of by a bulk and surface dual modification strategy developed in this work, where Cr doping modulates the Ru valence state in the bulk phase, suppressing Ru overoxidation, whereas Si modification stabilizes the reaction interface by inhibiting catalyst ...
Jiayi Tang, Zijun Fang, Yu‐Cheng Huang, Daqin Guan, Bin Chen, Zongping Shao   +5 more
wiley   +1 more source

Photocatalytic Water Splitting on the Lunar Surface: Prospects for In Situ Resource Utilization

Advanced Materials Interfaces, EarlyView.
Water has been found in craters on the moon nearby locations which are illuminated >80% of the time. Photocatalysis uses energy from sunlight to drive chemical reactions such as water splitting to produce oxygen and hydrogen. It is a scalable technology that requires lighter equipment and utilizes resources available on the moon. ABSTRACT The discovery
Ranjani Kalyan, Thomas D. Small, Gregory F. Metha, Mahmoud Adel Hamza, Thomas J. O'Dea, Yideng Shen, Cameron J. Shearer   +6 more
wiley   +1 more source

EEG-based classification in psychiatry using motif discovery

Neuroscience Informatics
In current medical practice, patients undergoing treatment for depression typically must wait four to six weeks before clinicians can assess their response to medication, due to the delayed onset of noticeable effects from antidepressants.
Melanija Kraljevska, Kateřina Hlaváčková-Schindler, Lukas Miklautz, Claudia Plant   +3 more
doaj   +1 more source

Chemically Doped Conductive Polymers for Wearable Health Monitoring

Advanced Materials Technologies, EarlyView.
Among conductive polymers, poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS), polyaniline (PANI), and polypyrrole (PPy) are the most studied and applied. Chemical doping significantly boosts intrinsic conductivity and mechanical robustness.
Mengdi Zuo, Jian Song, Hong Hu, Le Zheng, Lei Zhang, Charles H. Lawrie   +5 more
wiley   +1 more source

TADF‐Emitting Dendrimers for Scalable Bar‐Coating Fabrication of Light‐Emitting Electrochemical Cells

Advanced Materials Technologies, EarlyView.
TADF‐emitting dendrimers promise to enable scalable solution‐based fabrication of efficient electroluminescent devices by the virtue of an attractive set of properties. Here, we report on how light‐emitting electrochemical cells, comprising the TADF‐dendrimer tBuCz2m2pTRZ, can be fabricated by scalable bar‐coating under ambient air and deliver uniform ...
Shi Tang, Dianming Sun, Christian Larsen, Erik Zäll, Eli Zysman‐Colman, Ludvig Edman   +5 more
wiley   +1 more source

Preparation of a Brucella multiepitope fusion protein based on bioinformatics and its application in serological diagnosis of human brucellosis

Scientific Reports
Summary Brucellosis is a zoonotic infectious disease caused by the Brucella spp., and the enhancement of diagnostic techniques is imperative for effective disease control. Currently, the diagnosis of brucellosis predominantly relies on serological tests,
Guangyu Wang, Xinru Qi, Shiqi Zhao, Qichuan Pei, Yixiao Chen, Dehui Yin, Tiansong Zhan   +6 more
doaj   +1 more source

Direct Gravity‐Induced Modulation of Cardiac Conduction Pathways Evidenced Through Propagation Features in Electrophysiological Mapping

Advanced Materials Technologies, EarlyView.
A high‐density wearable body‐surface potential mapping array reveals how gravity reshapes cardiac conduction in real time. By resolving spatiotemporal delay patterns invisible to conventional ECG, the platform uncovers posture‐dependent electrophysiological adaptations across the thorax.
Ruben Ruiz‐Mateos Serrano, Matias L. Picchio, Daniele Mantione, David Mecerreyes, George G. Malliaras   +4 more
wiley   +1 more source