Results 71 to 80 of about 361,099 (313)
Herald of Khmelnytskyi National University. Technical sciencesThe article provides a comprehensive analysis of modern architectural approaches to software development using cloud technologies in the context of growing demands for scalability, fault tolerance, and security of information systems. It substantiates the relevance of the transition from traditional local deployment models to cloud environments that ...
OLHA KRAVCHUK +2 more
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mapping the Intersection of AI and Science Fiction: A Data-Driven Analysis Using R-Package
https://ieeexplore.ieee.org/abstract/document/10469114This study investigates the intersection between Artificial Intelligence (AI) and science fiction (Sci-Fi), using bibliometrix R-Package and VOSviewer network visualizations to analyze data from the ...
Quotah, Najlah, Sarirete, Akila
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Interference-Aware Routing for Difficult Wireless Sensor Network Environment with SWIPT
Sensors, 2019 The main challenges of sensing in harsh industrial and biological environments are the limited energy of sensor nodes and the difficulty of charging sensor nodes.
Shiming He +6 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Processes meet big data: connecting data science with process science
, 2015 As more and more companies are embracing Big data, it has become apparent that the ultimate challenge is to relate massive amounts of event data to processes that are highly dynamic. To unleash the value of event data, events need to be tightly connected
E. Damiani +5 more
core +1 more source